Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy

Treating Alzheimer’s disease, one of the most common neurodegenerative diseases, is of wide interest. Here, the authors report on the development of casein coated gold nanoparticles which were able to cross the blood brain barrier and protect against amyloid beta toxicity in a zebrafish model.

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Autores principales: Ibrahim Javed, Guotao Peng, Yanting Xing, Tianyu Yu, Mei Zhao, Aleksandr Kakinen, Ava Faridi, Clare L. Parish, Feng Ding, Thomas P. Davis, Pu Chun Ke, Sijie Lin
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e0577051f8ce4da6ad905f6a508a48cf
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spelling oai:doaj.org-article:e0577051f8ce4da6ad905f6a508a48cf2021-12-02T17:01:37ZInhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy10.1038/s41467-019-11762-02041-1723https://doaj.org/article/e0577051f8ce4da6ad905f6a508a48cf2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11762-0https://doaj.org/toc/2041-1723Treating Alzheimer’s disease, one of the most common neurodegenerative diseases, is of wide interest. Here, the authors report on the development of casein coated gold nanoparticles which were able to cross the blood brain barrier and protect against amyloid beta toxicity in a zebrafish model.Ibrahim JavedGuotao PengYanting XingTianyu YuMei ZhaoAleksandr KakinenAva FaridiClare L. ParishFeng DingThomas P. DavisPu Chun KeSijie LinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ibrahim Javed
Guotao Peng
Yanting Xing
Tianyu Yu
Mei Zhao
Aleksandr Kakinen
Ava Faridi
Clare L. Parish
Feng Ding
Thomas P. Davis
Pu Chun Ke
Sijie Lin
Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
description Treating Alzheimer’s disease, one of the most common neurodegenerative diseases, is of wide interest. Here, the authors report on the development of casein coated gold nanoparticles which were able to cross the blood brain barrier and protect against amyloid beta toxicity in a zebrafish model.
format article
author Ibrahim Javed
Guotao Peng
Yanting Xing
Tianyu Yu
Mei Zhao
Aleksandr Kakinen
Ava Faridi
Clare L. Parish
Feng Ding
Thomas P. Davis
Pu Chun Ke
Sijie Lin
author_facet Ibrahim Javed
Guotao Peng
Yanting Xing
Tianyu Yu
Mei Zhao
Aleksandr Kakinen
Ava Faridi
Clare L. Parish
Feng Ding
Thomas P. Davis
Pu Chun Ke
Sijie Lin
author_sort Ibrahim Javed
title Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
title_short Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
title_full Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
title_fullStr Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
title_full_unstemmed Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
title_sort inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e0577051f8ce4da6ad905f6a508a48cf
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