Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype
ABSTRACT Glycoprotein B (gB) is the conserved herpesvirus fusion protein, and it is required for the entry of herpesviruses. The structure of the postfusion conformation of gB has been solved for several herpesviruses; however, the gB prefusion crystal structure and the details of how the protein re...
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Autores principales: | Qing Fan, Sarah J. Kopp, Sarah A. Connolly, Richard Longnecker |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Acceso en línea: | https://doaj.org/article/e057c2425ccc426598f506f382c36731 |
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