Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p

Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p

Abstract Understanding mechanisms of resistance to abiraterone, one of the primary drugs approved for the treatment of castration resistant prostate cancer, remains a priority. The organic anion polypeptide 1B3 (OATP1B3, encoded by SLCO1B3) transporter has been shown to transport androgens into pros...

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Bibliographic Details
Main Authors: Roberto H. Barbier, Edel M. McCrea, Kristi Y. Lee, Jonathan D. Strope, Emily N. Risdon, Douglas K. Price, Cindy H. Chau, William D. Figg
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/e06fd1fa19174341a92b77d01fce5e9c
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