Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence
Abstract Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. The two predominant histologic variants of RMS, embryonal and alveolar rhabdomyosarcoma (eRMS and aRMS, respectively), carry very different prognoses. While eRMS is associated with an intermediate prognosis, the 5-year...
Guardado en:
Autores principales: | Jenny J. Li, Alexander R. Kovach, Margaret DeMonia, Katherine K. Slemmons, Kristianne M. Oristian, Candy Chen, Corinne M. Linardic |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e07c4697734344668dbd9b9c8ec6c4f3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Adult Cutaneous Rhabdomyosarcoma (RMS)
por: Vathana Ketheeswaranathan, et al.
Publicado: (2022) -
Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation
por: Michal Schwartz, et al.
Publicado: (2020) -
ZNF768 links oncogenic RAS to cellular senescence
por: Romain Villot, et al.
Publicado: (2021) -
Oncogene
Publicado: (1987) -
A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence.
por: Susanne Marije Kooistra, et al.
Publicado: (2014)