A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis

The ESCRT complex contributes to selective vacuolar degradation of membrane proteins. Here, the authors show that the plant-specific BRAF protein negatively regulates intraluminal vesicle formation and membrane protein degradation by preventing FREE1 binding to the ESCRT-I complex protein Vps23.

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Autores principales:	Jinbo Shen, Qiong Zhao, Xiangfeng Wang, Caiji Gao, Ying Zhu, Yonglun Zeng, Liwen Jiang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e07d09322bbf42ac97b3fb0813458d2b
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spelling	oai:doaj.org-article:e07d09322bbf42ac97b3fb0813458d2b2021-12-02T17:32:31ZA plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis10.1038/s41467-018-05913-y2041-1723https://doaj.org/article/e07d09322bbf42ac97b3fb0813458d2b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05913-yhttps://doaj.org/toc/2041-1723The ESCRT complex contributes to selective vacuolar degradation of membrane proteins. Here, the authors show that the plant-specific BRAF protein negatively regulates intraluminal vesicle formation and membrane protein degradation by preventing FREE1 binding to the ESCRT-I complex protein Vps23.Jinbo ShenQiong ZhaoXiangfeng WangCaiji GaoYing ZhuYonglun ZengLiwen JiangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jinbo Shen Qiong Zhao Xiangfeng Wang Caiji Gao Ying Zhu Yonglun Zeng Liwen Jiang A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
description	The ESCRT complex contributes to selective vacuolar degradation of membrane proteins. Here, the authors show that the plant-specific BRAF protein negatively regulates intraluminal vesicle formation and membrane protein degradation by preventing FREE1 binding to the ESCRT-I complex protein Vps23.
format	article
author	Jinbo Shen Qiong Zhao Xiangfeng Wang Caiji Gao Ying Zhu Yonglun Zeng Liwen Jiang
author_facet	Jinbo Shen Qiong Zhao Xiangfeng Wang Caiji Gao Ying Zhu Yonglun Zeng Liwen Jiang
author_sort	Jinbo Shen
title	A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
title_short	A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
title_full	A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
title_fullStr	A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
title_full_unstemmed	A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis
title_sort	plant bro1 domain protein braf regulates multivesicular body biogenesis and membrane protein homeostasis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e07d09322bbf42ac97b3fb0813458d2b
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A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis

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