Molecular-scale visualization of sarcomere contraction within native cardiomyocytes
Sarcomeres, the building blocks of striated muscles, comprise ordered actomyosin arrays involved in force production. Here, the authors visualize sarcomere organization in neonatal cardiomyocytes with in situ cryo-electron tomography, revealing a reduced order of the thin filaments, their sliding an...
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Main Authors: | Laura Burbaum, Jonathan Schneider, Sarah Scholze, Ralph T. Böttcher, Wolfgang Baumeister, Petra Schwille, Jürgen M. Plitzko, Marion Jasnin |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/e07d093c4c6e4c35be0d0751adcc87f0 |
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