Exploring microsatellite instability in patients with advanced hepatocellular carcinoma and its tumor microenvironment

Exploring microsatellite instability in patients with advanced hepatocellular carcinoma and its tumor microenvironment

Abstract Background and Aim Immune checkpoint inhibitors and their combination with other agents have recently been available in advanced hepatocellular carcinoma (HCC). Hence, a thorough understanding of the tumor microenvironment based on tumor samples is yet to be achieved. This study aimed to ex...

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Autores principales: Shohei Mukai, Hiroaki Kanzaki, Sadahisa Ogasawara, Takamasa Ishino, Keita Ogawa, Miyuki Nakagawa, Kisako Fujiwara, Hidemi Unozawa, Terunao Iwanaga, Takafumi Sakuma, Naoto Fujita, Keisuke Koroki, Kazufumi Kobayashi, Naoya Kanogawa, Soichiro Kiyono, Masato Nakamura, Takayuki Kondo, Tomoko Saito, Ryo Nakagawa, Eiichiro Suzuki, Yoshihiko Ooka, Ryosuke Muroyama, Shingo Nakamoto, Akinobu Tawada, Tetsuhiro Chiba, Makoto Arai, Jun Kato, Manayu Shiina, Masayuki Ota, Jun‐ichiro Ikeda, Yuichi Takiguchi, Masayuki Ohtsuka, Naoya Kato
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
Materias:
hepatocellular carcinoma
microsatellite instability
mismatch repair
PD‐L1
tumor microenvironment
Diseases of the digestive system. Gastroenterology
RC799-869
Acceso en línea:https://doaj.org/article/e082e4c91a2142358c016fb7ff695a59
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https://doaj.org/article/e082e4c91a2142358c016fb7ff695a59

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