Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.

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Autores principales:	Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn, W. Andy Tao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e083ebec23fd4782a7cf7d04711ee3c2
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spelling	oai:doaj.org-article:e083ebec23fd4782a7cf7d04711ee3c22021-12-02T17:06:35ZChemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor10.1038/s41467-020-17638-y2041-1723https://doaj.org/article/e083ebec23fd4782a7cf7d04711ee3c22020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17638-yhttps://doaj.org/toc/2041-1723The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.Mayank SrivastavaYing ZhangJian ChenDevika SirohiAndrew MillerYang ZhangZhilu ChenHaojie LuJianqing XuRichard J. KuhnW. Andy TaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mayank Srivastava Ying Zhang Jian Chen Devika Sirohi Andrew Miller Yang Zhang Zhilu Chen Haojie Lu Jianqing Xu Richard J. Kuhn W. Andy Tao Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
description	The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.
format	article
author	Mayank Srivastava Ying Zhang Jian Chen Devika Sirohi Andrew Miller Yang Zhang Zhilu Chen Haojie Lu Jianqing Xu Richard J. Kuhn W. Andy Tao
author_facet	Mayank Srivastava Ying Zhang Jian Chen Devika Sirohi Andrew Miller Yang Zhang Zhilu Chen Haojie Lu Jianqing Xu Richard J. Kuhn W. Andy Tao
author_sort	Mayank Srivastava
title	Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
title_short	Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
title_full	Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
title_fullStr	Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
title_full_unstemmed	Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
title_sort	chemical proteomics tracks virus entry and uncovers ncam1 as zika virus receptor
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e083ebec23fd4782a7cf7d04711ee3c2
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Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

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