Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.

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Autores principales: Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn, W. Andy Tao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/e083ebec23fd4782a7cf7d04711ee3c2
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