Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.

Toxocariasis is worldwide endemic parasitic anthropozoonosis with high risk to those in in vulnerable populations and particularly during pregnancy and childhood. Although the prevalence of anti-Toxocara spp. antibodies has been extensively studied, risk factors of pregnant women of different ages r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Priscila de Oliveira Azevedo, Susana Zevallos Lescano, Rogério Giuffrida, Louise Bach Kmetiuk, Andrea Pires Dos Santos, Sriveny Dangoudoubiyam, Alexander Welker Biondo, Vamilton Alvares Santarém
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/e08872eaaab34b528d7640a2b63a7365
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e08872eaaab34b528d7640a2b63a7365
record_format	dspace
spelling	oai:doaj.org-article:e08872eaaab34b528d7640a2b63a73652021-12-02T20:23:42ZSerosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.1935-27271935-273510.1371/journal.pntd.0009571https://doaj.org/article/e08872eaaab34b528d7640a2b63a73652021-08-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009571https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735Toxocariasis is worldwide endemic parasitic anthropozoonosis with high risk to those in in vulnerable populations and particularly during pregnancy and childhood. Although the prevalence of anti-Toxocara spp. antibodies has been extensively studied, risk factors of pregnant women of different ages remains to be established. This study was designed to i) assess the presence of anti-Toxocara spp. antibodies in pregnant women that presented to the public health system in a city of southeastern Brazil, and ii) determine the risk factors for toxocariasis in adolescent and adult pregnant women. This cross-sectional study included 280 pregnant women (71 aged up to and including 17 years [adolescents] and 209 aged 18 years and older [adults]). Pregnant women voluntarily agreed to complete a socioeconomic questionnaire and provide serum samples. Anti-Toxocara IgG antibodies were screened by Enzyme-Linked Immunosorbent Assay (ELISA). Univariable and multivariable logistic regression models were performed to assess the risks for toxocariasis. Overall, 20.7% of pregnant women were seropositive (33.8% of adolescents and 16.3% of adults). Prevalence in pregnant adolescents was 2.6-fold higher than in adults (Odds ration [OR]: 2.63; 95% CI: 1.42-4.86, p = 0.003). Multivariate analysis revealed that contact with soil (p = 0.01; OR = 4.76) and being in the first trimester of pregnancy (p = 0.03; OR = 0.17) had significantly greater risk of toxocariasis for adolescents, and attainment of elementary through middle school education level (p = 0.05; OR = 8.33) was a risk factor in adult pregnant women. Toxocariasis is likely underreported and neglected in adolescent pregnant women; this age group should always be monitored for toxocariasis and correspondent clinical signs, particularly at late pregnancy.Priscila de Oliveira AzevedoSusana Zevallos LescanoRogério GiuffridaLouise Bach KmetiukAndrea Pires Dos SantosSriveny DangoudoubiyamAlexander Welker BiondoVamilton Alvares SantarémPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009571 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
spellingShingle	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Priscila de Oliveira Azevedo Susana Zevallos Lescano Rogério Giuffrida Louise Bach Kmetiuk Andrea Pires Dos Santos Sriveny Dangoudoubiyam Alexander Welker Biondo Vamilton Alvares Santarém Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
description	Toxocariasis is worldwide endemic parasitic anthropozoonosis with high risk to those in in vulnerable populations and particularly during pregnancy and childhood. Although the prevalence of anti-Toxocara spp. antibodies has been extensively studied, risk factors of pregnant women of different ages remains to be established. This study was designed to i) assess the presence of anti-Toxocara spp. antibodies in pregnant women that presented to the public health system in a city of southeastern Brazil, and ii) determine the risk factors for toxocariasis in adolescent and adult pregnant women. This cross-sectional study included 280 pregnant women (71 aged up to and including 17 years [adolescents] and 209 aged 18 years and older [adults]). Pregnant women voluntarily agreed to complete a socioeconomic questionnaire and provide serum samples. Anti-Toxocara IgG antibodies were screened by Enzyme-Linked Immunosorbent Assay (ELISA). Univariable and multivariable logistic regression models were performed to assess the risks for toxocariasis. Overall, 20.7% of pregnant women were seropositive (33.8% of adolescents and 16.3% of adults). Prevalence in pregnant adolescents was 2.6-fold higher than in adults (Odds ration [OR]: 2.63; 95% CI: 1.42-4.86, p = 0.003). Multivariate analysis revealed that contact with soil (p = 0.01; OR = 4.76) and being in the first trimester of pregnancy (p = 0.03; OR = 0.17) had significantly greater risk of toxocariasis for adolescents, and attainment of elementary through middle school education level (p = 0.05; OR = 8.33) was a risk factor in adult pregnant women. Toxocariasis is likely underreported and neglected in adolescent pregnant women; this age group should always be monitored for toxocariasis and correspondent clinical signs, particularly at late pregnancy.
format	article
author	Priscila de Oliveira Azevedo Susana Zevallos Lescano Rogério Giuffrida Louise Bach Kmetiuk Andrea Pires Dos Santos Sriveny Dangoudoubiyam Alexander Welker Biondo Vamilton Alvares Santarém
author_facet	Priscila de Oliveira Azevedo Susana Zevallos Lescano Rogério Giuffrida Louise Bach Kmetiuk Andrea Pires Dos Santos Sriveny Dangoudoubiyam Alexander Welker Biondo Vamilton Alvares Santarém
author_sort	Priscila de Oliveira Azevedo
title	Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
title_short	Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
title_full	Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
title_fullStr	Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
title_full_unstemmed	Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.
title_sort	serosurvey of anti-toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern brazil.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/e08872eaaab34b528d7640a2b63a7365
work_keys_str_mv	AT prisciladeoliveiraazevedo serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT susanazevalloslescano serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT rogeriogiuffrida serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT louisebachkmetiuk serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT andreapiresdossantos serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT srivenydangoudoubiyam serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT alexanderwelkerbiondo serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil AT vamiltonalvaressantarem serosurveyofantitoxocaraantibodiesandriskfactorsinadolescentandadultpregnantwomenofsoutheasternbrazil
_version_	1718374138323664896

Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil.

Ejemplares similares