Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to threaten agriculture and human health. Here, we use biochemistry and x-ray crystallography to reveal how amino-acid variations in the hemagglutinin (HA) protein contribute to the pathogenicity of H5N1 influenza virus in chicke...
Guardado en:
Autores principales: | Rebecca M DuBois, Hassan Zaraket, Muralidhar Reddivari, Richard J Heath, Stephen W White, Charles J Russell |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e09d4bebb97d49c48a30c6137ade9502 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Relationship between hemagglutinin stability and influenza virus persistence after exposure to low pH or supraphysiological heating.
por: Guohua Yang, et al.
Publicado: (2021) -
Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics
por: Eili Y. Klein, et al.
Publicado: (2018) -
Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses
por: Christopher L. D. McMillan, et al.
Publicado: (2021) -
Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.
por: Karunya Srinivasan, et al.
Publicado: (2013) -
Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin
por: Naganori Nao, et al.
Publicado: (2017)