Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to threaten agriculture and human health. Here, we use biochemistry and x-ray crystallography to reveal how amino-acid variations in the hemagglutinin (HA) protein contribute to the pathogenicity of H5N1 influenza virus in chicke...
Enregistré dans:
Auteurs principaux: | Rebecca M DuBois, Hassan Zaraket, Muralidhar Reddivari, Richard J Heath, Stephen W White, Charles J Russell |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/e09d4bebb97d49c48a30c6137ade9502 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Relationship between hemagglutinin stability and influenza virus persistence after exposure to low pH or supraphysiological heating.
par: Guohua Yang, et autres
Publié: (2021) -
Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics
par: Eili Y. Klein, et autres
Publié: (2018) -
Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses
par: Christopher L. D. McMillan, et autres
Publié: (2021) -
Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.
par: Karunya Srinivasan, et autres
Publié: (2013) -
Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin
par: Naganori Nao, et autres
Publié: (2017)