Fibroblast fusion to the muscle fiber regulates myotendinous junction formation

Classically, myogenic precursor cells derive from somites, and connective tissues derive from lateral plate mesoderm (LPM). Here the authors identify LPM derived fibroblasts that turn on a myogenic program and fuse to muscle fibers at muscle-tendon junctions, introducing fibroblast transcripts into...

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Autores principales:	Wesal Yaseen, Ortal Kraft-Sheleg, Shelly Zaffryar-Eilot, Shay Melamed, Chengyi Sun, Douglas P. Millay, Peleg Hasson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e0a89d8052694add8716e21454d9a0e1
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spelling	oai:doaj.org-article:e0a89d8052694add8716e21454d9a0e12021-12-02T18:02:47ZFibroblast fusion to the muscle fiber regulates myotendinous junction formation10.1038/s41467-021-24159-92041-1723https://doaj.org/article/e0a89d8052694add8716e21454d9a0e12021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24159-9https://doaj.org/toc/2041-1723Classically, myogenic precursor cells derive from somites, and connective tissues derive from lateral plate mesoderm (LPM). Here the authors identify LPM derived fibroblasts that turn on a myogenic program and fuse to muscle fibers at muscle-tendon junctions, introducing fibroblast transcripts into myofibers.Wesal YaseenOrtal Kraft-ShelegShelly Zaffryar-EilotShay MelamedChengyi SunDouglas P. MillayPeleg HassonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wesal Yaseen Ortal Kraft-Sheleg Shelly Zaffryar-Eilot Shay Melamed Chengyi Sun Douglas P. Millay Peleg Hasson Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
description	Classically, myogenic precursor cells derive from somites, and connective tissues derive from lateral plate mesoderm (LPM). Here the authors identify LPM derived fibroblasts that turn on a myogenic program and fuse to muscle fibers at muscle-tendon junctions, introducing fibroblast transcripts into myofibers.
format	article
author	Wesal Yaseen Ortal Kraft-Sheleg Shelly Zaffryar-Eilot Shay Melamed Chengyi Sun Douglas P. Millay Peleg Hasson
author_facet	Wesal Yaseen Ortal Kraft-Sheleg Shelly Zaffryar-Eilot Shay Melamed Chengyi Sun Douglas P. Millay Peleg Hasson
author_sort	Wesal Yaseen
title	Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
title_short	Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
title_full	Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
title_fullStr	Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
title_full_unstemmed	Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
title_sort	fibroblast fusion to the muscle fiber regulates myotendinous junction formation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e0a89d8052694add8716e21454d9a0e1
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Fibroblast fusion to the muscle fiber regulates myotendinous junction formation

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