A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution

Mexican Tetra cavefish have long been of interest in understanding adaptation to severe environmental change. Here the authors present a chromosome-level genome for the proxy-ancestral surface fish, and use CRISPR gene-editing to show the role of the rx3 gene in eye size.

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Autores principales: Wesley C. Warren, Tyler E. Boggs, Richard Borowsky, Brian M. Carlson, Estephany Ferrufino, Joshua B. Gross, LaDeana Hillier, Zhilian Hu, Alex C. Keene, Alexander Kenzior, Johanna E. Kowalko, Chad Tomlinson, Milinn Kremitzki, Madeleine E. Lemieux, Tina Graves-Lindsay, Suzanne E. McGaugh, Jeffrey T. Miller, Mathilda T. M. Mommersteeg, Rachel L. Moran, Robert Peuß, Edward S. Rice, Misty R. Riddle, Itzel Sifuentes-Romero, Bethany A. Stanhope, Clifford J. Tabin, Sunishka Thakur, Yoshiyuki Yamamoto, Nicolas Rohner
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e0b3331ea2974ca4af008dc49760b084
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spelling oai:doaj.org-article:e0b3331ea2974ca4af008dc49760b0842021-12-02T15:52:50ZA chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution10.1038/s41467-021-21733-z2041-1723https://doaj.org/article/e0b3331ea2974ca4af008dc49760b0842021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21733-zhttps://doaj.org/toc/2041-1723Mexican Tetra cavefish have long been of interest in understanding adaptation to severe environmental change. Here the authors present a chromosome-level genome for the proxy-ancestral surface fish, and use CRISPR gene-editing to show the role of the rx3 gene in eye size.Wesley C. WarrenTyler E. BoggsRichard BorowskyBrian M. CarlsonEstephany FerrufinoJoshua B. GrossLaDeana HillierZhilian HuAlex C. KeeneAlexander KenziorJohanna E. KowalkoChad TomlinsonMilinn KremitzkiMadeleine E. LemieuxTina Graves-LindsaySuzanne E. McGaughJeffrey T. MillerMathilda T. M. MommersteegRachel L. MoranRobert PeußEdward S. RiceMisty R. RiddleItzel Sifuentes-RomeroBethany A. StanhopeClifford J. TabinSunishka ThakurYoshiyuki YamamotoNicolas RohnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wesley C. Warren
Tyler E. Boggs
Richard Borowsky
Brian M. Carlson
Estephany Ferrufino
Joshua B. Gross
LaDeana Hillier
Zhilian Hu
Alex C. Keene
Alexander Kenzior
Johanna E. Kowalko
Chad Tomlinson
Milinn Kremitzki
Madeleine E. Lemieux
Tina Graves-Lindsay
Suzanne E. McGaugh
Jeffrey T. Miller
Mathilda T. M. Mommersteeg
Rachel L. Moran
Robert Peuß
Edward S. Rice
Misty R. Riddle
Itzel Sifuentes-Romero
Bethany A. Stanhope
Clifford J. Tabin
Sunishka Thakur
Yoshiyuki Yamamoto
Nicolas Rohner
A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
description Mexican Tetra cavefish have long been of interest in understanding adaptation to severe environmental change. Here the authors present a chromosome-level genome for the proxy-ancestral surface fish, and use CRISPR gene-editing to show the role of the rx3 gene in eye size.
format article
author Wesley C. Warren
Tyler E. Boggs
Richard Borowsky
Brian M. Carlson
Estephany Ferrufino
Joshua B. Gross
LaDeana Hillier
Zhilian Hu
Alex C. Keene
Alexander Kenzior
Johanna E. Kowalko
Chad Tomlinson
Milinn Kremitzki
Madeleine E. Lemieux
Tina Graves-Lindsay
Suzanne E. McGaugh
Jeffrey T. Miller
Mathilda T. M. Mommersteeg
Rachel L. Moran
Robert Peuß
Edward S. Rice
Misty R. Riddle
Itzel Sifuentes-Romero
Bethany A. Stanhope
Clifford J. Tabin
Sunishka Thakur
Yoshiyuki Yamamoto
Nicolas Rohner
author_facet Wesley C. Warren
Tyler E. Boggs
Richard Borowsky
Brian M. Carlson
Estephany Ferrufino
Joshua B. Gross
LaDeana Hillier
Zhilian Hu
Alex C. Keene
Alexander Kenzior
Johanna E. Kowalko
Chad Tomlinson
Milinn Kremitzki
Madeleine E. Lemieux
Tina Graves-Lindsay
Suzanne E. McGaugh
Jeffrey T. Miller
Mathilda T. M. Mommersteeg
Rachel L. Moran
Robert Peuß
Edward S. Rice
Misty R. Riddle
Itzel Sifuentes-Romero
Bethany A. Stanhope
Clifford J. Tabin
Sunishka Thakur
Yoshiyuki Yamamoto
Nicolas Rohner
author_sort Wesley C. Warren
title A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
title_short A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
title_full A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
title_fullStr A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
title_full_unstemmed A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
title_sort chromosome-level genome of astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e0b3331ea2974ca4af008dc49760b084
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