Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures.

Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal role in intercellular communication by regulating recipient cell gene expression and affecting target cell function. Here, we report the isolation of three distinct EV subtypes from the human colon carcinoma cell...

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Auteurs principaux: Hong Ji, Maoshan Chen, David W Greening, Weifeng He, Alin Rai, Wenwei Zhang, Richard J Simpson
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/e0c039f11c2740e8a1863b69cb261a59
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