Dopaminergic dynamics underlying sex-specific cocaine reward

Sex differences in reward processing are at present poorly understood. Calipari and Juarezet al. report oestrous cycle-dependent fluctuations in firing of VTA dopamine neurons that drive alterations in DAT function expressed in terminals in the NAc. These differences underlie enhanced cocaine reward...

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Autores principales:	Erin S. Calipari, Barbara Juarez, Carole Morel, Deena M. Walker, Michael E. Cahill, Efrain Ribeiro, Ciorana Roman-Ortiz, Charu Ramakrishnan, Karl Deisseroth, Ming-Hu Han, Eric J Nestler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e0c9ffcc0e3446528630e91b45a3633a
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spelling	oai:doaj.org-article:e0c9ffcc0e3446528630e91b45a3633a2021-12-02T17:06:27ZDopaminergic dynamics underlying sex-specific cocaine reward10.1038/ncomms138772041-1723https://doaj.org/article/e0c9ffcc0e3446528630e91b45a3633a2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13877https://doaj.org/toc/2041-1723Sex differences in reward processing are at present poorly understood. Calipari and Juarezet al. report oestrous cycle-dependent fluctuations in firing of VTA dopamine neurons that drive alterations in DAT function expressed in terminals in the NAc. These differences underlie enhanced cocaine reward processing during oestrus.Erin S. CalipariBarbara JuarezCarole MorelDeena M. WalkerMichael E. CahillEfrain RibeiroCiorana Roman-OrtizCharu RamakrishnanKarl DeisserothMing-Hu HanEric J NestlerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erin S. Calipari Barbara Juarez Carole Morel Deena M. Walker Michael E. Cahill Efrain Ribeiro Ciorana Roman-Ortiz Charu Ramakrishnan Karl Deisseroth Ming-Hu Han Eric J Nestler Dopaminergic dynamics underlying sex-specific cocaine reward
description	Sex differences in reward processing are at present poorly understood. Calipari and Juarezet al. report oestrous cycle-dependent fluctuations in firing of VTA dopamine neurons that drive alterations in DAT function expressed in terminals in the NAc. These differences underlie enhanced cocaine reward processing during oestrus.
format	article
author	Erin S. Calipari Barbara Juarez Carole Morel Deena M. Walker Michael E. Cahill Efrain Ribeiro Ciorana Roman-Ortiz Charu Ramakrishnan Karl Deisseroth Ming-Hu Han Eric J Nestler
author_facet	Erin S. Calipari Barbara Juarez Carole Morel Deena M. Walker Michael E. Cahill Efrain Ribeiro Ciorana Roman-Ortiz Charu Ramakrishnan Karl Deisseroth Ming-Hu Han Eric J Nestler
author_sort	Erin S. Calipari
title	Dopaminergic dynamics underlying sex-specific cocaine reward
title_short	Dopaminergic dynamics underlying sex-specific cocaine reward
title_full	Dopaminergic dynamics underlying sex-specific cocaine reward
title_fullStr	Dopaminergic dynamics underlying sex-specific cocaine reward
title_full_unstemmed	Dopaminergic dynamics underlying sex-specific cocaine reward
title_sort	dopaminergic dynamics underlying sex-specific cocaine reward
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e0c9ffcc0e3446528630e91b45a3633a
work_keys_str_mv	AT erinscalipari dopaminergicdynamicsunderlyingsexspecificcocainereward AT barbarajuarez dopaminergicdynamicsunderlyingsexspecificcocainereward AT carolemorel dopaminergicdynamicsunderlyingsexspecificcocainereward AT deenamwalker dopaminergicdynamicsunderlyingsexspecificcocainereward AT michaelecahill dopaminergicdynamicsunderlyingsexspecificcocainereward AT efrainribeiro dopaminergicdynamicsunderlyingsexspecificcocainereward AT cioranaromanortiz dopaminergicdynamicsunderlyingsexspecificcocainereward AT charuramakrishnan dopaminergicdynamicsunderlyingsexspecificcocainereward AT karldeisseroth dopaminergicdynamicsunderlyingsexspecificcocainereward AT minghuhan dopaminergicdynamicsunderlyingsexspecificcocainereward AT ericjnestler dopaminergicdynamicsunderlyingsexspecificcocainereward
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Dopaminergic dynamics underlying sex-specific cocaine reward

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