3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery

3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the...

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Autores principales:	Rafaela Santos de Oliveira, Stephani Silva Fantaus, Antonio José Guillot, Ana Melero, Ruy Carlos Ruver Beck
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	additive manufacturing wound dressing FDM skin disorders film patch Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/e0ccd2c756874d1fa72c4b8ac814aa8e
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spelling	oai:doaj.org-article:e0ccd2c756874d1fa72c4b8ac814aa8e2021-11-25T18:42:15Z3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery10.3390/pharmaceutics131119461999-4923https://doaj.org/article/e0ccd2c756874d1fa72c4b8ac814aa8e2021-11-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1946https://doaj.org/toc/1999-49233D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the use of 3D printing for the development of pharmaceutical and biomedical products for topical skin applications, covering plain dressing and products for the delivery of active ingredients to the skin. Based on the data acquired, the important growth in the number of publications over the last years confirms its interest. The semisolid extrusion technique has been the most reported one, probably because it allows the use of a broad range of polymers, creating the most diverse therapeutic approaches. 3D printing has been an excellent field for customizing dressings, according to individual needs. Studies discussed here imply the use of metals, nanoparticles, drugs, natural compounds and proteins and peptides for the treatment of wound healing, acne, pain relief, and anti-wrinkle, among others. The confluence of 3D printing and topical applications has undeniable advantages, and we would like to encourage the research groups to explore this field to improve the patient’s life quality, adherence and treatment efficacy.Rafaela Santos de OliveiraStephani Silva FantausAntonio José GuillotAna MeleroRuy Carlos Ruver BeckMDPI AGarticleadditive manufacturingwound dressingFDMskin disordersfilmpatchPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1946, p 1946 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	additive manufacturing wound dressing FDM skin disorders film patch Pharmacy and materia medica RS1-441
spellingShingle	additive manufacturing wound dressing FDM skin disorders film patch Pharmacy and materia medica RS1-441 Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
description	3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the use of 3D printing for the development of pharmaceutical and biomedical products for topical skin applications, covering plain dressing and products for the delivery of active ingredients to the skin. Based on the data acquired, the important growth in the number of publications over the last years confirms its interest. The semisolid extrusion technique has been the most reported one, probably because it allows the use of a broad range of polymers, creating the most diverse therapeutic approaches. 3D printing has been an excellent field for customizing dressings, according to individual needs. Studies discussed here imply the use of metals, nanoparticles, drugs, natural compounds and proteins and peptides for the treatment of wound healing, acne, pain relief, and anti-wrinkle, among others. The confluence of 3D printing and topical applications has undeniable advantages, and we would like to encourage the research groups to explore this field to improve the patient’s life quality, adherence and treatment efficacy.
format	article
author	Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck
author_facet	Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck
author_sort	Rafaela Santos de Oliveira
title	3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
title_short	3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
title_full	3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
title_fullStr	3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
title_full_unstemmed	3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
title_sort	3d-printed products for topical skin applications: from personalized dressings to drug delivery
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/e0ccd2c756874d1fa72c4b8ac814aa8e
work_keys_str_mv	AT rafaelasantosdeoliveira 3dprintedproductsfortopicalskinapplicationsfrompersonalizeddressingstodrugdelivery AT stephanisilvafantaus 3dprintedproductsfortopicalskinapplicationsfrompersonalizeddressingstodrugdelivery AT antoniojoseguillot 3dprintedproductsfortopicalskinapplicationsfrompersonalizeddressingstodrugdelivery AT anamelero 3dprintedproductsfortopicalskinapplicationsfrompersonalizeddressingstodrugdelivery AT ruycarlosruverbeck 3dprintedproductsfortopicalskinapplicationsfrompersonalizeddressingstodrugdelivery
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3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery

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