Loss of the transcription factor MAFB limits β-cell derivation from human PSCs
The MAF bZIP transcription factor B (MAFB) is present in postnatal human beta cells but its role is unclear. Here, the authors show that MAFB regulates endocrine pancreatic cell fate specification.
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Autores principales: | Ronan Russell, Phichitpol P. Carnese, Thomas G. Hennings, Emily M. Walker, Holger A. Russ, Jennifer S. Liu, Simone Giacometti, Roland Stein, Matthias Hebrok |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/e0d2c3d6cf86401bb280695fe609017c |
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