Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction.

Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction.

<h4>Background</h4>In chronic liver disease, hepatic stellate cells (HSC) transdifferentiate into myofibroblasts, promoting extracellular matrix (ECM) synthesis and deposition. Stimulation of HSC by transforming growth factor-β (TGF-β) is a crucial event in liver fibrogenesis due to its...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Monika Kwiecinski, Andrea Noetel, Natalia Elfimova, Jonel Trebicka, Stephanie Schievenbusch, Ingo Strack, Levente Molnar, Melanie von Brandenstein, Ulrich Töx, Roswitha Nischt, Oliver Coutelle, Hans Peter Dienes, Margarete Odenthal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e0d98e2590fe47cead544574a88526b9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares