Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure.
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Nature Portfolio
2020
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oai:doaj.org-article:e0ded77076c64ae2ae577ea0a33bd6c22021-12-02T14:41:26ZLipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness10.1038/s41467-020-15203-12041-1723https://doaj.org/article/e0ded77076c64ae2ae577ea0a33bd6c22020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15203-1https://doaj.org/toc/2041-1723Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure.Kandice R. LeventalEric MalmbergJessica L. SymonsYang-Yi FanRobert S. ChapkinRobert ErnstIlya LeventalNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Kandice R. Levental Eric Malmberg Jessica L. Symons Yang-Yi Fan Robert S. Chapkin Robert Ernst Ilya Levental Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
description |
Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure. |
format |
article |
author |
Kandice R. Levental Eric Malmberg Jessica L. Symons Yang-Yi Fan Robert S. Chapkin Robert Ernst Ilya Levental |
author_facet |
Kandice R. Levental Eric Malmberg Jessica L. Symons Yang-Yi Fan Robert S. Chapkin Robert Ernst Ilya Levental |
author_sort |
Kandice R. Levental |
title |
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
title_short |
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
title_full |
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
title_fullStr |
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
title_full_unstemmed |
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
title_sort |
lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/e0ded77076c64ae2ae577ea0a33bd6c2 |
work_keys_str_mv |
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1718389903260123136 |