Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure.

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Autores principales: Kandice R. Levental, Eric Malmberg, Jessica L. Symons, Yang-Yi Fan, Robert S. Chapkin, Robert Ernst, Ilya Levental
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e0ded77076c64ae2ae577ea0a33bd6c2
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spelling oai:doaj.org-article:e0ded77076c64ae2ae577ea0a33bd6c22021-12-02T14:41:26ZLipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness10.1038/s41467-020-15203-12041-1723https://doaj.org/article/e0ded77076c64ae2ae577ea0a33bd6c22020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15203-1https://doaj.org/toc/2041-1723Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure.Kandice R. LeventalEric MalmbergJessica L. SymonsYang-Yi FanRobert S. ChapkinRobert ErnstIlya LeventalNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kandice R. Levental
Eric Malmberg
Jessica L. Symons
Yang-Yi Fan
Robert S. Chapkin
Robert Ernst
Ilya Levental
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
description Proper membrane physiology requires maintenance of a narrow range of physicochemical properties, which must be buffered from external perturbations. Here, authors report lipidomic remodeling to preserve membrane physical properties upon exogenous polyunsaturated fatty acids exposure.
format article
author Kandice R. Levental
Eric Malmberg
Jessica L. Symons
Yang-Yi Fan
Robert S. Chapkin
Robert Ernst
Ilya Levental
author_facet Kandice R. Levental
Eric Malmberg
Jessica L. Symons
Yang-Yi Fan
Robert S. Chapkin
Robert Ernst
Ilya Levental
author_sort Kandice R. Levental
title Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
title_short Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
title_full Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
title_fullStr Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
title_full_unstemmed Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
title_sort lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e0ded77076c64ae2ae577ea0a33bd6c2
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