Examining the current standards for genetic discovery and replication in the era of mega-biobanks

Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits the standards for discovery, replication and fol...

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Autor principal: J. E. Huffman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e0e9cfc2fb5a45499502d4c6039df67a
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Sumario:Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits the standards for discovery, replication and follow-up in GWAS today.