Examining the current standards for genetic discovery and replication in the era of mega-biobanks

Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits the standards for discovery, replication and fol...

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Autor principal:	J. E. Huffman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e0e9cfc2fb5a45499502d4c6039df67a
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spelling	oai:doaj.org-article:e0e9cfc2fb5a45499502d4c6039df67a2021-12-02T17:31:31ZExamining the current standards for genetic discovery and replication in the era of mega-biobanks10.1038/s41467-018-07348-x2041-1723https://doaj.org/article/e0e9cfc2fb5a45499502d4c6039df67a2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07348-xhttps://doaj.org/toc/2041-1723Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits the standards for discovery, replication and follow-up in GWAS today.J. E. HuffmanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-4 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q J. E. Huffman Examining the current standards for genetic discovery and replication in the era of mega-biobanks
description	Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits the standards for discovery, replication and follow-up in GWAS today.
format	article
author	J. E. Huffman
author_facet	J. E. Huffman
author_sort	J. E. Huffman
title	Examining the current standards for genetic discovery and replication in the era of mega-biobanks
title_short	Examining the current standards for genetic discovery and replication in the era of mega-biobanks
title_full	Examining the current standards for genetic discovery and replication in the era of mega-biobanks
title_fullStr	Examining the current standards for genetic discovery and replication in the era of mega-biobanks
title_full_unstemmed	Examining the current standards for genetic discovery and replication in the era of mega-biobanks
title_sort	examining the current standards for genetic discovery and replication in the era of mega-biobanks
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e0e9cfc2fb5a45499502d4c6039df67a
work_keys_str_mv	AT jehuffman examiningthecurrentstandardsforgeneticdiscoveryandreplicationintheeraofmegabiobanks
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Examining the current standards for genetic discovery and replication in the era of mega-biobanks

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