Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆

Microbial-based biodiesel is produced by transesterification of lipids extracted from microbial cells, and is considered as a potential replacement of fossil fuel due to its advantages in reducing greenhouse gas emissions. Yarrowia lipolytica is one of the most studied oleaginous yeasts able to prod...

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Autores principales: El Kantar Sally, Khelfa Anissa, Vorobiev Eugène, Koubaa Mohamed
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Publicado: EDP Sciences 2021
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spelling oai:doaj.org-article:e0f124eaf3054853b079d905d56289852021-12-02T17:14:29ZStrategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆2272-69772257-661410.1051/ocl/2021038https://doaj.org/article/e0f124eaf3054853b079d905d56289852021-01-01T00:00:00Zhttps://www.ocl-journal.org/articles/ocl/full_html/2021/01/ocl210051/ocl210051.htmlhttps://doaj.org/toc/2272-6977https://doaj.org/toc/2257-6614Microbial-based biodiesel is produced by transesterification of lipids extracted from microbial cells, and is considered as a potential replacement of fossil fuel due to its advantages in reducing greenhouse gas emissions. Yarrowia lipolytica is one of the most studied oleaginous yeasts able to produce lipids under some fermentation conditions and is considered as a potential industrial host for biodiesel production. Several approaches have been evaluated to increase the economical attraction of biodiesel production from Y. lipolytica lipids. In this review, we highlighted the different strategies reported in the literature, allowing this yeast to achieve high lipid accumulation. These include metabolic engineering strategies, the use of low-cost effective substrates, and the optimization of the cultivation conditions for higher lipid productivity and less operating cost. We also summarized the most effective cell disruption technologies that improve the extraction efficiencies of lipids from Y. lipolytica.El Kantar SallyKhelfa AnissaVorobiev EugèneKoubaa MohamedEDP Sciencesarticley. lipolyticamicrobial oilslipid accumulationlipid extractionbiodieselOils, fats, and waxesTP670-699ENFROilseeds and fats, crops and lipids, Vol 28, p 51 (2021)
institution DOAJ
collection DOAJ
language EN
FR
topic y. lipolytica
microbial oils
lipid accumulation
lipid extraction
biodiesel
Oils, fats, and waxes
TP670-699
spellingShingle y. lipolytica
microbial oils
lipid accumulation
lipid extraction
biodiesel
Oils, fats, and waxes
TP670-699
El Kantar Sally
Khelfa Anissa
Vorobiev Eugène
Koubaa Mohamed
Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
description Microbial-based biodiesel is produced by transesterification of lipids extracted from microbial cells, and is considered as a potential replacement of fossil fuel due to its advantages in reducing greenhouse gas emissions. Yarrowia lipolytica is one of the most studied oleaginous yeasts able to produce lipids under some fermentation conditions and is considered as a potential industrial host for biodiesel production. Several approaches have been evaluated to increase the economical attraction of biodiesel production from Y. lipolytica lipids. In this review, we highlighted the different strategies reported in the literature, allowing this yeast to achieve high lipid accumulation. These include metabolic engineering strategies, the use of low-cost effective substrates, and the optimization of the cultivation conditions for higher lipid productivity and less operating cost. We also summarized the most effective cell disruption technologies that improve the extraction efficiencies of lipids from Y. lipolytica.
format article
author El Kantar Sally
Khelfa Anissa
Vorobiev Eugène
Koubaa Mohamed
author_facet El Kantar Sally
Khelfa Anissa
Vorobiev Eugène
Koubaa Mohamed
author_sort El Kantar Sally
title Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
title_short Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
title_full Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
title_fullStr Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
title_full_unstemmed Strategies for increasing lipid accumulation and recovery from Y. lipolytica: A review☆
title_sort strategies for increasing lipid accumulation and recovery from y. lipolytica: a review☆
publisher EDP Sciences
publishDate 2021
url https://doaj.org/article/e0f124eaf3054853b079d905d5628985
work_keys_str_mv AT elkantarsally strategiesforincreasinglipidaccumulationandrecoveryfromylipolyticaareview
AT khelfaanissa strategiesforincreasinglipidaccumulationandrecoveryfromylipolyticaareview
AT vorobieveugene strategiesforincreasinglipidaccumulationandrecoveryfromylipolyticaareview
AT koubaamohamed strategiesforincreasinglipidaccumulationandrecoveryfromylipolyticaareview
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