FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Fernandes et al. discover a connection between the mitochondrial stress response and genomic stability. They find that transcription of common fragile site (CFS) genes is induced by mitochondrial stress, whereas a regulator of CFS stability, FANCD2, acts to dampen the mitochondrial stress response a...
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Autores principales: | Philippe Fernandes, Benoit Miotto, Claude Saint-Ruf, Maha Said, Viviana Barra, Viola Nähse, Silvia Ravera, Enrico Cappelli, Valeria Naim |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e0f19b4840814983bdab55f7127e98cd |
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