Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation

Abstract Objective We investigated the long-term visual outcomes and ocular complications of primary scleral-fixated posterior chamber intraocular lenses (SF-PC-IOLs) in patients with congenital lens subluxation. Methods We enrolled 53 patients (77 eyes) with congenital lens subluxation caused by ec...

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Autores principales:	Anjian Wang, Qi Fan, Yongxiang Jiang, Yi Lu
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Congenital lens subluxation Long-term follow-up Postoperative eye trauma Scleral-fixated posterior chamber intraocular lens Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e0f56b07fab24f82b76d4dd69413b86f
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spelling	oai:doaj.org-article:e0f56b07fab24f82b76d4dd69413b86f2021-12-05T12:26:35ZPrimary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation10.1186/s12886-021-02182-01471-2415https://doaj.org/article/e0f56b07fab24f82b76d4dd69413b86f2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12886-021-02182-0https://doaj.org/toc/1471-2415Abstract Objective We investigated the long-term visual outcomes and ocular complications of primary scleral-fixated posterior chamber intraocular lenses (SF-PC-IOLs) in patients with congenital lens subluxation. Methods We enrolled 53 patients (77 eyes) with congenital lens subluxation caused by ectopia lentis, Marfan syndrome, and Weill–Marchesani syndrome who underwent primary implantation of a SF-PC-IOL. All patients underwent a complete ophthalmic examination include visual acuity (VA), intraocular pressure (IOP), intraocular lenses (IOL) position, intraoperative complications and postoperative complications. Cox regression analysis and survival analysis were used to evaluate the risk factors for postoperative complications. Results Seventy seven eyes from 53 patients were included. Mean age at surgery was 23 ± 20 years (5 to 67 years), with a mean follow-up of 39 ± 27 months (12 to 130 months). The best-corrected VA improved from 0.84 ± 0.55 to 0.26 ± 0.43 logarithms of the minimum angle of resolution (p < 0.001). Best-corrected VA improved postoperatively in 73 eyes (94%). The main causes of reduced vision after surgery were retinal pathologies and amblyopia. Complications included transient intraocular haemorrhage (2 eyes, 2.6%), early vitreous incarceration (2 eyes, 2.6%), retinal detachment (6 eyes, 7.8%) and IOL dislocation (3 eyes, 3.9%). Cox regression showed that postoperative eye trauma was a risk factor for long-term postoperative complications. Conclusion SF-PC-IOLs provide good visual outcomes in patients with congenital lens subluxation. The SF-PC-IOLs showed good stability, except in patients suffering from postsurgical eye trauma.Anjian WangQi FanYongxiang JiangYi LuBMCarticleCongenital lens subluxationLong-term follow-upPostoperative eye traumaScleral-fixated posterior chamber intraocular lensOphthalmologyRE1-994ENBMC Ophthalmology, Vol 21, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Congenital lens subluxation Long-term follow-up Postoperative eye trauma Scleral-fixated posterior chamber intraocular lens Ophthalmology RE1-994
spellingShingle	Congenital lens subluxation Long-term follow-up Postoperative eye trauma Scleral-fixated posterior chamber intraocular lens Ophthalmology RE1-994 Anjian Wang Qi Fan Yongxiang Jiang Yi Lu Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
description	Abstract Objective We investigated the long-term visual outcomes and ocular complications of primary scleral-fixated posterior chamber intraocular lenses (SF-PC-IOLs) in patients with congenital lens subluxation. Methods We enrolled 53 patients (77 eyes) with congenital lens subluxation caused by ectopia lentis, Marfan syndrome, and Weill–Marchesani syndrome who underwent primary implantation of a SF-PC-IOL. All patients underwent a complete ophthalmic examination include visual acuity (VA), intraocular pressure (IOP), intraocular lenses (IOL) position, intraoperative complications and postoperative complications. Cox regression analysis and survival analysis were used to evaluate the risk factors for postoperative complications. Results Seventy seven eyes from 53 patients were included. Mean age at surgery was 23 ± 20 years (5 to 67 years), with a mean follow-up of 39 ± 27 months (12 to 130 months). The best-corrected VA improved from 0.84 ± 0.55 to 0.26 ± 0.43 logarithms of the minimum angle of resolution (p < 0.001). Best-corrected VA improved postoperatively in 73 eyes (94%). The main causes of reduced vision after surgery were retinal pathologies and amblyopia. Complications included transient intraocular haemorrhage (2 eyes, 2.6%), early vitreous incarceration (2 eyes, 2.6%), retinal detachment (6 eyes, 7.8%) and IOL dislocation (3 eyes, 3.9%). Cox regression showed that postoperative eye trauma was a risk factor for long-term postoperative complications. Conclusion SF-PC-IOLs provide good visual outcomes in patients with congenital lens subluxation. The SF-PC-IOLs showed good stability, except in patients suffering from postsurgical eye trauma.
format	article
author	Anjian Wang Qi Fan Yongxiang Jiang Yi Lu
author_facet	Anjian Wang Qi Fan Yongxiang Jiang Yi Lu
author_sort	Anjian Wang
title	Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
title_short	Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
title_full	Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
title_fullStr	Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
title_full_unstemmed	Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
title_sort	primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation
publisher	BMC
publishDate	2021
url	https://doaj.org/article/e0f56b07fab24f82b76d4dd69413b86f
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Primary scleral-fixated posterior chamber intraocular lenses in patients with congenital lens subluxation

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