Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation
ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected cells and induces angiogenesis. In this study, we sh...
Guardado en:
Autores principales: | Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e112ec564a7b40c191ff06dc9080fbc1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34<sup>+</sup> Hematopoietic Progenitor Cells and Humanized NSG Mice
por: Lindsey B. Crawford, et al.
Publicado: (2019) -
UL146 variability among clinical isolates of Human Cytomegalovirus from Japan
por: Aguayo,Francisco, et al.
Publicado: (2010) -
The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus
por: Sigrun Häge, et al.
Publicado: (2021) -
Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and <italic toggle="yes">UL138</italic> Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways
por: Meaghan H. Hancock, et al.
Publicado: (2020) -
Pseudogene fms-related tyrosine kinase 1 pseudogene 1 (FLT1P1) cooperates with RNA binding protein dyskeratosis congenita 1 (DKC1) to restrain trophoblast cell proliferation and angiogenesis by targeting fms-related tyrosine kinase 1 (FLT1) in preeclampsia
por: Zhenjing Chi, et al.
Publicado: (2021)