EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE

Objective: To determine the efficacy of atorvastatin in reducing proteinuria in patients of chronic kidney disease. Study Design: Quasi experimental study. Place and Duration of Study: Combined Military Hospital Multan, from Jan 2014 to Jun 2014. Material and Methods: Seventy patients of bo...

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Autores principales:	Rizwan Azam, Ejaz Ahmed, Asad Raza, Mahwish Rizwan, Ali Jamal, Syed Salman Ali
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	atorvastatin chronic kidney disease efficacy Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e114ee44175f46adb5e160ccc7fb473d
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spelling	oai:doaj.org-article:e114ee44175f46adb5e160ccc7fb473d2021-11-11T04:32:46ZEFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE0030-96482411-8842https://doaj.org/article/e114ee44175f46adb5e160ccc7fb473d2019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3206/2315https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the efficacy of atorvastatin in reducing proteinuria in patients of chronic kidney disease. Study Design: Quasi experimental study. Place and Duration of Study: Combined Military Hospital Multan, from Jan 2014 to Jun 2014. Material and Methods: Seventy patients of both genders with documented chronic kidney disease (GFR <90>15ml/min) for at least 3 months duration were included by non-probability consecutive sampling. Age of the patients and reduction in proteinuria from the baseline after using atorvastatin was noted. The data were analyzed by using SPSS v 19. Descriptive statistics like mean ± SD, percentages and frequencies were calculated for age and efficacy of atorvastatin. The data collected for study was statistically analyzed using chi-square test. Results: The overall efficacy of atorvastatin was 31.43%. Twenty two out of 70 subjects had significant reduction in proteinuria i.e.>0.25 gm/24 hrs from baseline after statin use. A significant statistical association was not seen in the efficacy of atorvastatin between males and females, p-value being >0.05. Conclusion: A notable number of patients had improvement in their 24 hours proteinuria after the use of atorvastatin. Therefore atorvastatin use may be beneficial in all patients of chronic kidney disease as it will reduce progression of the disease and prevent rate of decline in renal functioning.Rizwan AzamEjaz AhmedAsad RazaMahwish RizwanAli JamalSyed Salman AliArmy Medical College Rawalpindiarticleatorvastatinchronic kidney diseaseefficacyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 818-821 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	atorvastatin chronic kidney disease efficacy Medicine R Medicine (General) R5-920
spellingShingle	atorvastatin chronic kidney disease efficacy Medicine R Medicine (General) R5-920 Rizwan Azam Ejaz Ahmed Asad Raza Mahwish Rizwan Ali Jamal Syed Salman Ali EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
description	Objective: To determine the efficacy of atorvastatin in reducing proteinuria in patients of chronic kidney disease. Study Design: Quasi experimental study. Place and Duration of Study: Combined Military Hospital Multan, from Jan 2014 to Jun 2014. Material and Methods: Seventy patients of both genders with documented chronic kidney disease (GFR <90>15ml/min) for at least 3 months duration were included by non-probability consecutive sampling. Age of the patients and reduction in proteinuria from the baseline after using atorvastatin was noted. The data were analyzed by using SPSS v 19. Descriptive statistics like mean ± SD, percentages and frequencies were calculated for age and efficacy of atorvastatin. The data collected for study was statistically analyzed using chi-square test. Results: The overall efficacy of atorvastatin was 31.43%. Twenty two out of 70 subjects had significant reduction in proteinuria i.e.>0.25 gm/24 hrs from baseline after statin use. A significant statistical association was not seen in the efficacy of atorvastatin between males and females, p-value being >0.05. Conclusion: A notable number of patients had improvement in their 24 hours proteinuria after the use of atorvastatin. Therefore atorvastatin use may be beneficial in all patients of chronic kidney disease as it will reduce progression of the disease and prevent rate of decline in renal functioning.
format	article
author	Rizwan Azam Ejaz Ahmed Asad Raza Mahwish Rizwan Ali Jamal Syed Salman Ali
author_facet	Rizwan Azam Ejaz Ahmed Asad Raza Mahwish Rizwan Ali Jamal Syed Salman Ali
author_sort	Rizwan Azam
title	EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
title_short	EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
title_full	EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
title_fullStr	EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
title_full_unstemmed	EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE
title_sort	efficacy of atorvastatin in reducing proteinuria in patients of chronic kidney disease
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/e114ee44175f46adb5e160ccc7fb473d
work_keys_str_mv	AT rizwanazam efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease AT ejazahmed efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease AT asadraza efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease AT mahwishrizwan efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease AT alijamal efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease AT syedsalmanali efficacyofatorvastatininreducingproteinuriainpatientsofchronickidneydisease
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EFFICACY OF ATORVASTATIN IN REDUCING PROTEINURIA IN PATIENTS OF CHRONIC KIDNEY DISEASE

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