Developmental activities of the complement pathway in migrating neurons

Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.

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Autores principales: Anna Gorelik, Tamar Sapir, Rebecca Haffner-Krausz, Tsviya Olender, Trent M. Woodruff, Orly Reiner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e11dc61947534819a52c2923baf9b313
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spelling oai:doaj.org-article:e11dc61947534819a52c2923baf9b3132021-12-02T14:41:11ZDevelopmental activities of the complement pathway in migrating neurons10.1038/ncomms150962041-1723https://doaj.org/article/e11dc61947534819a52c2923baf9b3132017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15096https://doaj.org/toc/2041-1723Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.Anna GorelikTamar SapirRebecca Haffner-KrauszTsviya OlenderTrent M. WoodruffOrly ReinerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anna Gorelik
Tamar Sapir
Rebecca Haffner-Krausz
Tsviya Olender
Trent M. Woodruff
Orly Reiner
Developmental activities of the complement pathway in migrating neurons
description Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.
format article
author Anna Gorelik
Tamar Sapir
Rebecca Haffner-Krausz
Tsviya Olender
Trent M. Woodruff
Orly Reiner
author_facet Anna Gorelik
Tamar Sapir
Rebecca Haffner-Krausz
Tsviya Olender
Trent M. Woodruff
Orly Reiner
author_sort Anna Gorelik
title Developmental activities of the complement pathway in migrating neurons
title_short Developmental activities of the complement pathway in migrating neurons
title_full Developmental activities of the complement pathway in migrating neurons
title_fullStr Developmental activities of the complement pathway in migrating neurons
title_full_unstemmed Developmental activities of the complement pathway in migrating neurons
title_sort developmental activities of the complement pathway in migrating neurons
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e11dc61947534819a52c2923baf9b313
work_keys_str_mv AT annagorelik developmentalactivitiesofthecomplementpathwayinmigratingneurons
AT tamarsapir developmentalactivitiesofthecomplementpathwayinmigratingneurons
AT rebeccahaffnerkrausz developmentalactivitiesofthecomplementpathwayinmigratingneurons
AT tsviyaolender developmentalactivitiesofthecomplementpathwayinmigratingneurons
AT trentmwoodruff developmentalactivitiesofthecomplementpathwayinmigratingneurons
AT orlyreiner developmentalactivitiesofthecomplementpathwayinmigratingneurons
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