Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates

Background and Objective: Hepatitis B vaccination is one of the effective way to prevent and control this disease. With regard to its importance in children and intervention of different factors in vaccine efficacy, this study was done to determine the role of birth weight in production of anti HBS...

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Autores principales:	MR Esmaili Duki, Y ZahedPasha, A Mahdavi, M Haji Ahmadi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2003
Materias:	vaccination hepatitis b low birth weight Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e123fc4838d14c9e8c106fe7704ff606
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spelling	oai:doaj.org-article:e123fc4838d14c9e8c106fe7704ff6062021-11-10T09:18:07ZComparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates1561-41072251-7170https://doaj.org/article/e123fc4838d14c9e8c106fe7704ff6062003-04-01T00:00:00Zhttp://jbums.org/article-1-2767-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Hepatitis B vaccination is one of the effective way to prevent and control this disease. With regard to its importance in children and intervention of different factors in vaccine efficacy, this study was done to determine the role of birth weight in production of anti HBS after routine programming of vaccination in our country. Methods: This analytical study was performed on 120 children under 7 years old who referred Amirkola children hospital during 2000-2001. They were divided into two groups: Low birth weight or ≤2500g0r (Group A) and normal birth weight or more than 2500gr (Group B). Findings: From all studied children, 40 cases were in group A (25 males and 15 females) and 80 cases were in group B (43 males, 35 females and 2 children were excluded). Mean age was almost the same in both groups. In group A, 36 cases (90%) had protective level of Anti-HBS (>10 mIu/ml) and in 4 cases (10%), Anti-HBS levels were less. In group B, the protective levels of Anti-HBS had been produced in all of the children (P=0.012). But, there was not a significant difference between protective levels of Anti-HBS in group A and expected response in children (95%). The mean of Anti-HBS levels in group A was 182.1±45.1 mIu/ml and in group B was 334.7±41.4 mIu/ml (P=0.014). Conclusion: The protective levels of Anti-HBS in low birth weight group were lower than normal birth weight group. Since, there was not a significant difference between this response in LBW and ideal response in children, it is recommended to continue routine vaccination in LBW like normal birth weight infants.MR Esmaili DukiY ZahedPashaA MahdaviM Haji AhmadiBabol University of Medical Sciencesarticlevaccinationhepatitis blow birth weightMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 5, Iss 2, Pp 14-18 (2003)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	vaccination hepatitis b low birth weight Medicine R Medicine (General) R5-920
spellingShingle	vaccination hepatitis b low birth weight Medicine R Medicine (General) R5-920 MR Esmaili Duki Y ZahedPasha A Mahdavi M Haji Ahmadi Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
description	Background and Objective: Hepatitis B vaccination is one of the effective way to prevent and control this disease. With regard to its importance in children and intervention of different factors in vaccine efficacy, this study was done to determine the role of birth weight in production of anti HBS after routine programming of vaccination in our country. Methods: This analytical study was performed on 120 children under 7 years old who referred Amirkola children hospital during 2000-2001. They were divided into two groups: Low birth weight or ≤2500g0r (Group A) and normal birth weight or more than 2500gr (Group B). Findings: From all studied children, 40 cases were in group A (25 males and 15 females) and 80 cases were in group B (43 males, 35 females and 2 children were excluded). Mean age was almost the same in both groups. In group A, 36 cases (90%) had protective level of Anti-HBS (>10 mIu/ml) and in 4 cases (10%), Anti-HBS levels were less. In group B, the protective levels of Anti-HBS had been produced in all of the children (P=0.012). But, there was not a significant difference between protective levels of Anti-HBS in group A and expected response in children (95%). The mean of Anti-HBS levels in group A was 182.1±45.1 mIu/ml and in group B was 334.7±41.4 mIu/ml (P=0.014). Conclusion: The protective levels of Anti-HBS in low birth weight group were lower than normal birth weight group. Since, there was not a significant difference between this response in LBW and ideal response in children, it is recommended to continue routine vaccination in LBW like normal birth weight infants.
format	article
author	MR Esmaili Duki Y ZahedPasha A Mahdavi M Haji Ahmadi
author_facet	MR Esmaili Duki Y ZahedPasha A Mahdavi M Haji Ahmadi
author_sort	MR Esmaili Duki
title	Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
title_short	Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
title_full	Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
title_fullStr	Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
title_full_unstemmed	Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates
title_sort	comparison of the effect of hepatitis b vaccination in normal and low birth weight neonates
publisher	Babol University of Medical Sciences
publishDate	2003
url	https://doaj.org/article/e123fc4838d14c9e8c106fe7704ff606
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Comparison of the effect of Hepatitis B vaccination in normal and low birth weight neonates

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