Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress

Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, &l...

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Autores principales: Elisa Martello, Francesca Perondi, Natascia Bruni, Donal Bisanzio, Giorgia Meineri, Ilaria Lippi
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
CKD
dog
ROS
Acceso en línea:https://doaj.org/article/e125b321655e4fa1998e19e959280d73
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spelling oai:doaj.org-article:e125b321655e4fa1998e19e959280d732021-11-25T19:12:06ZChronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress10.3390/vetsci81102772306-7381https://doaj.org/article/e125b321655e4fa1998e19e959280d732021-11-01T00:00:00Zhttps://www.mdpi.com/2306-7381/8/11/277https://doaj.org/toc/2306-7381Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, <i>Olea europaea</i> L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.Elisa MartelloFrancesca PerondiNatascia BruniDonal BisanzioGiorgia MeineriIlaria LippiMDPI AGarticleCKDdogdiet supplementserum phosphorusSDMAROSVeterinary medicineSF600-1100ENVeterinary Sciences, Vol 8, Iss 277, p 277 (2021)
institution DOAJ
collection DOAJ
language EN
topic CKD
dog
diet supplement
serum phosphorus
SDMA
ROS
Veterinary medicine
SF600-1100
spellingShingle CKD
dog
diet supplement
serum phosphorus
SDMA
ROS
Veterinary medicine
SF600-1100
Elisa Martello
Francesca Perondi
Natascia Bruni
Donal Bisanzio
Giorgia Meineri
Ilaria Lippi
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
description Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, <i>Olea europaea</i> L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.
format article
author Elisa Martello
Francesca Perondi
Natascia Bruni
Donal Bisanzio
Giorgia Meineri
Ilaria Lippi
author_facet Elisa Martello
Francesca Perondi
Natascia Bruni
Donal Bisanzio
Giorgia Meineri
Ilaria Lippi
author_sort Elisa Martello
title Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
title_short Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
title_full Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
title_fullStr Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
title_full_unstemmed Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
title_sort chronic kidney disease and dietary supplementation: effects on inflammation and oxidative stress
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/e125b321655e4fa1998e19e959280d73
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