Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress
Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, &l...
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MDPI AG
2021
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oai:doaj.org-article:e125b321655e4fa1998e19e959280d732021-11-25T19:12:06ZChronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress10.3390/vetsci81102772306-7381https://doaj.org/article/e125b321655e4fa1998e19e959280d732021-11-01T00:00:00Zhttps://www.mdpi.com/2306-7381/8/11/277https://doaj.org/toc/2306-7381Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, <i>Olea europaea</i> L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.Elisa MartelloFrancesca PerondiNatascia BruniDonal BisanzioGiorgia MeineriIlaria LippiMDPI AGarticleCKDdogdiet supplementserum phosphorusSDMAROSVeterinary medicineSF600-1100ENVeterinary Sciences, Vol 8, Iss 277, p 277 (2021) |
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CKD dog diet supplement serum phosphorus SDMA ROS Veterinary medicine SF600-1100 |
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CKD dog diet supplement serum phosphorus SDMA ROS Veterinary medicine SF600-1100 Elisa Martello Francesca Perondi Natascia Bruni Donal Bisanzio Giorgia Meineri Ilaria Lippi Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
description |
Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, <i>Olea europaea</i> L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD. |
format |
article |
author |
Elisa Martello Francesca Perondi Natascia Bruni Donal Bisanzio Giorgia Meineri Ilaria Lippi |
author_facet |
Elisa Martello Francesca Perondi Natascia Bruni Donal Bisanzio Giorgia Meineri Ilaria Lippi |
author_sort |
Elisa Martello |
title |
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
title_short |
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
title_full |
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
title_fullStr |
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
title_full_unstemmed |
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress |
title_sort |
chronic kidney disease and dietary supplementation: effects on inflammation and oxidative stress |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/e125b321655e4fa1998e19e959280d73 |
work_keys_str_mv |
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