EGR-2 is not required for in vivo CD4 T cell mediated immune responses.
<h4>Background</h4>The zinc finger transcription factor EGR-2 has been shown to play an important role in the induction of T cell anergy and the regulation of peripheral T cell tolerance. In vitro, a prior study has show that T cells deficient in EGR-2 are hyperproliferative to IL-2 and...
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Autores principales: | Hilda E Ramón, Pedro J Cejas, David LaRosa, Adeeb Rahman, John E Harris, Jidong Zhang, Christopher Hunter, Yongwon Choi, Laurence A Turka |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/e12be66e2b8442d0b9e35c38c7646539 |
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