Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3
Abstract Systemic hypoxia is a common element in most perinatal emergencies and is a known driver of Bnip3 expression in the neonatal heart. Bnip3 plays a prominent role in the evolution of necrotic cell death, disrupting ER calcium homeostasis and initiating mitochondrial permeability transition (M...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Nature Publishing Group
2021
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| Accès en ligne: | https://doaj.org/article/e1343dcb2c5b484c91d04a2bde3e5a8e |
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