Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls

Linlin Sun,1,2 Chunli Zheng,3 Thomas J Webster1,2,4 1Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 3Pharmaceutical Research Instit...

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Autores principales:	Sun L, Zheng C, Webster TJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	self-assembly peptides biomedical applications drug delivery antibacterial therapy biosensor devices Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e138e144b6d4465a8d11cacc3e6139c7
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spelling	oai:doaj.org-article:e138e144b6d4465a8d11cacc3e6139c72021-12-02T00:40:24ZSelf-assembled peptide nanomaterials for biomedical applications: promises and pitfalls1178-2013https://doaj.org/article/e138e144b6d4465a8d11cacc3e6139c72016-12-01T00:00:00Zhttps://www.dovepress.com/self-assembled-peptide-nanomaterials-for-biomedical-applications-promi-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Linlin Sun,1,2 Chunli Zheng,3 Thomas J Webster1,2,4 1Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 3Pharmaceutical Research Institute, China Pharmaceutical University, Nanjing, People’s Republic of China; 4Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: Over the last several decades, a great number of advances have been made in the area of self-assembled supramolecules for regenerative medicine. Such advances have involved the design, preparation, and characterization of brand new self-assembled peptide nanomaterials for a variety of applications. Among all biomolecules considered for self-assembly applications, peptides have attracted a great deal of attention as building blocks for bottom-up fabrication, due to their versatility, ease of manufacturing, low costs, tunable structures, and versatile properties. Herein, some of the more exciting new designs of self-assembled peptides and their associated unique features are reviewed and several promising applications of how self-assembled peptides are advancing drug delivery, tissue engineering, antibacterial therapy, and biosensor device applications are highlighted. Keywords: self-assembly, peptides, biomedical applications, drug delivery, antibacterial therapy, biosensor devicesSun LZheng CWebster TJDove Medical Pressarticleself-assemblypeptidesbiomedical applicationsdrug deliveryantibacterial therapybiosensor devicesMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 73-86 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	self-assembly peptides biomedical applications drug delivery antibacterial therapy biosensor devices Medicine (General) R5-920
spellingShingle	self-assembly peptides biomedical applications drug delivery antibacterial therapy biosensor devices Medicine (General) R5-920 Sun L Zheng C Webster TJ Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
description	Linlin Sun,1,2 Chunli Zheng,3 Thomas J Webster1,2,4 1Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 3Pharmaceutical Research Institute, China Pharmaceutical University, Nanjing, People’s Republic of China; 4Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: Over the last several decades, a great number of advances have been made in the area of self-assembled supramolecules for regenerative medicine. Such advances have involved the design, preparation, and characterization of brand new self-assembled peptide nanomaterials for a variety of applications. Among all biomolecules considered for self-assembly applications, peptides have attracted a great deal of attention as building blocks for bottom-up fabrication, due to their versatility, ease of manufacturing, low costs, tunable structures, and versatile properties. Herein, some of the more exciting new designs of self-assembled peptides and their associated unique features are reviewed and several promising applications of how self-assembled peptides are advancing drug delivery, tissue engineering, antibacterial therapy, and biosensor device applications are highlighted. Keywords: self-assembly, peptides, biomedical applications, drug delivery, antibacterial therapy, biosensor devices
format	article
author	Sun L Zheng C Webster TJ
author_facet	Sun L Zheng C Webster TJ
author_sort	Sun L
title	Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
title_short	Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
title_full	Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
title_fullStr	Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
title_full_unstemmed	Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
title_sort	self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/e138e144b6d4465a8d11cacc3e6139c7
work_keys_str_mv	AT sunl selfassembledpeptidenanomaterialsforbiomedicalapplicationspromisesandpitfalls AT zhengc selfassembledpeptidenanomaterialsforbiomedicalapplicationspromisesandpitfalls AT webstertj selfassembledpeptidenanomaterialsforbiomedicalapplicationspromisesandpitfalls
_version_	1718403588695261184

Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls

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