An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions,...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b |
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| Résumé: | Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions, including co-culture systems. |
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