An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients

Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions,...

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Autores principales:	Anne C. Gilmore, Sarah J. Flaherty, Veena Somasundaram, David A. Scheiblin, Stephen J. Lockett, David A. Wink, William F. Heinz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b
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spelling	oai:doaj.org-article:e13ab04655bc4d119008eaaf1d13d34b2021-12-02T18:03:20ZAn in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients10.1038/s42003-021-01954-02399-3642https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01954-0https://doaj.org/toc/2399-3642Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions, including co-culture systems.Anne C. GilmoreSarah J. FlahertyVeena SomasundaramDavid A. ScheiblinStephen J. LockettDavid A. WinkWilliam F. HeinzNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Anne C. Gilmore Sarah J. Flaherty Veena Somasundaram David A. Scheiblin Stephen J. Lockett David A. Wink William F. Heinz An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
description	Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions, including co-culture systems.
format	article
author	Anne C. Gilmore Sarah J. Flaherty Veena Somasundaram David A. Scheiblin Stephen J. Lockett David A. Wink William F. Heinz
author_facet	Anne C. Gilmore Sarah J. Flaherty Veena Somasundaram David A. Scheiblin Stephen J. Lockett David A. Wink William F. Heinz
author_sort	Anne C. Gilmore
title	An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
title_short	An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
title_full	An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
title_fullStr	An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
title_full_unstemmed	An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
title_sort	in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b
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An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients

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