An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differentially developed tumour microenvironment conditions,...
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Main Authors: | Anne C. Gilmore, Sarah J. Flaherty, Veena Somasundaram, David A. Scheiblin, Stephen J. Lockett, David A. Wink, William F. Heinz |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b |
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