Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion

Abstract We previously identified the inhibitory serpin protease nexin-1 (PN-1) as an important player of the angiogenic balance with anti-angiogenic activity in physiological conditions. In the present study, we aimed to determine the role of PN-1 on pathological angiogenesis and particularly in re...

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Autores principales: Sonia Selbonne, Celina Madjene, Benjamin Salmon, Yacine Boulaftali, Marie-Christine Bouton, Véronique Arocas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e13bbebf55f44816aa7f01fcf805e533
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