Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants

Diosgenin is a spiroketal natural product that is used as a precursor in the industrial synthesis of steroids. Here, the authors identified key cytochrome P450 enzymes responsible for the conversion of cholesterol to diosgenin from two phylogenetical distinct diosgenin-producing plant species.

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Detalles Bibliográficos
Autores principales: Bastien Christ, Chengchao Xu, Menglong Xu, Fu-Shuang Li, Naoki Wada, Andrew J. Mitchell, Xiu-Lin Han, Meng-Liang Wen, Makoto Fujita, Jing-Ke Weng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e13c38f37d8b4fb285caa3dbbf0a5a77
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Sumario:Diosgenin is a spiroketal natural product that is used as a precursor in the industrial synthesis of steroids. Here, the authors identified key cytochrome P450 enzymes responsible for the conversion of cholesterol to diosgenin from two phylogenetical distinct diosgenin-producing plant species.