Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome.

Proline is an anomalous amino acid. Its nitrogen atom is covalently locked within a ring, thus it is the only proteinogenic amino acid with a constrained phi angle. Sequences of three consecutive prolines can fold into polyproline helices, structures that join alpha helices and beta pleats as archit...

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Autores principales: Alexander A Morgan, Edward Rubenstein
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/e1409044fc1f4bc09326a079c6907427
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