Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

The signals restricting specification of vascular progenitors are unclear. Here, the authors use scRNAseq to identify transitional steps during blood and vascular development in zebrafish and identify Etv2 as repressing skeletal muscle differentiation in vascular progenitors.

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Autores principales:	Brendan Chestnut, Satish Casie Chetty, Andrew L. Koenig, Saulius Sumanas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e1441094e0f94f03917601c570752e35
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spelling	oai:doaj.org-article:e1441094e0f94f03917601c570752e352021-12-02T15:03:03ZSingle-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle10.1038/s41467-020-16515-y2041-1723https://doaj.org/article/e1441094e0f94f03917601c570752e352020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16515-yhttps://doaj.org/toc/2041-1723The signals restricting specification of vascular progenitors are unclear. Here, the authors use scRNAseq to identify transitional steps during blood and vascular development in zebrafish and identify Etv2 as repressing skeletal muscle differentiation in vascular progenitors.Brendan ChestnutSatish Casie ChettyAndrew L. KoenigSaulius SumanasNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brendan Chestnut Satish Casie Chetty Andrew L. Koenig Saulius Sumanas Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
description	The signals restricting specification of vascular progenitors are unclear. Here, the authors use scRNAseq to identify transitional steps during blood and vascular development in zebrafish and identify Etv2 as repressing skeletal muscle differentiation in vascular progenitors.
format	article
author	Brendan Chestnut Satish Casie Chetty Andrew L. Koenig Saulius Sumanas
author_facet	Brendan Chestnut Satish Casie Chetty Andrew L. Koenig Saulius Sumanas
author_sort	Brendan Chestnut
title	Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
title_short	Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
title_full	Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
title_fullStr	Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
title_full_unstemmed	Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
title_sort	single-cell transcriptomic analysis identifies the conversion of zebrafish etv2-deficient vascular progenitors into skeletal muscle
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e1441094e0f94f03917601c570752e35
work_keys_str_mv	AT brendanchestnut singlecelltranscriptomicanalysisidentifiestheconversionofzebrafishetv2deficientvascularprogenitorsintoskeletalmuscle AT satishcasiechetty singlecelltranscriptomicanalysisidentifiestheconversionofzebrafishetv2deficientvascularprogenitorsintoskeletalmuscle AT andrewlkoenig singlecelltranscriptomicanalysisidentifiestheconversionofzebrafishetv2deficientvascularprogenitorsintoskeletalmuscle AT sauliussumanas singlecelltranscriptomicanalysisidentifiestheconversionofzebrafishetv2deficientvascularprogenitorsintoskeletalmuscle
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Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

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