Modulation of Interleukin-12 activity in the presence of heparin

Modulation of Interleukin-12 activity in the presence of heparin

Abstract Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine the mechanism(s) by which heparin influences IL-12 b...

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Bibliographic Details
Main Authors: Srinivas Jayanthi, Bhanu prasanth Koppolu, Khue G. Nguyen, Sean G. Smith, Barbara K. Felber, Thallapuranam Krishnaswamy Suresh Kumar, David A. Zaharoff
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e144fa0271714f01b788c20adf60ba9f
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