Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants

Mariangela Cavarelli et al. utilize cynomolgus macaque colorectal tissue explants to explore the effect of leukocytospermic seminal plasma (LSP) on SIVmac251 infection. Their results suggest that mucosal SIV infection is influenced by the inflammatory state of the semen donor, providing further insi...

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Autores principales: Mariangela Cavarelli, Stéphane Hua, Naima Hantour, Sabine Tricot, Nicolas Tchitchek, Céline Gommet, Hakim Hocini, Catherine Chapon, Nathalie Dereuddre-Bosquet, Roger Le Grand
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e148333ddf904b1ea51de80c040200ca
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spelling oai:doaj.org-article:e148333ddf904b1ea51de80c040200ca2021-12-02T15:32:57ZLeukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants10.1038/s42003-021-02383-92399-3642https://doaj.org/article/e148333ddf904b1ea51de80c040200ca2021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02383-9https://doaj.org/toc/2399-3642Mariangela Cavarelli et al. utilize cynomolgus macaque colorectal tissue explants to explore the effect of leukocytospermic seminal plasma (LSP) on SIVmac251 infection. Their results suggest that mucosal SIV infection is influenced by the inflammatory state of the semen donor, providing further insight into mucosal SIV pathogenesis.Mariangela CavarelliStéphane HuaNaima HantourSabine TricotNicolas TchitchekCéline GommetHakim HociniCatherine ChaponNathalie Dereuddre-BosquetRoger Le GrandNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mariangela Cavarelli
Stéphane Hua
Naima Hantour
Sabine Tricot
Nicolas Tchitchek
Céline Gommet
Hakim Hocini
Catherine Chapon
Nathalie Dereuddre-Bosquet
Roger Le Grand
Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
description Mariangela Cavarelli et al. utilize cynomolgus macaque colorectal tissue explants to explore the effect of leukocytospermic seminal plasma (LSP) on SIVmac251 infection. Their results suggest that mucosal SIV infection is influenced by the inflammatory state of the semen donor, providing further insight into mucosal SIV pathogenesis.
format article
author Mariangela Cavarelli
Stéphane Hua
Naima Hantour
Sabine Tricot
Nicolas Tchitchek
Céline Gommet
Hakim Hocini
Catherine Chapon
Nathalie Dereuddre-Bosquet
Roger Le Grand
author_facet Mariangela Cavarelli
Stéphane Hua
Naima Hantour
Sabine Tricot
Nicolas Tchitchek
Céline Gommet
Hakim Hocini
Catherine Chapon
Nathalie Dereuddre-Bosquet
Roger Le Grand
author_sort Mariangela Cavarelli
title Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
title_short Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
title_full Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
title_fullStr Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
title_full_unstemmed Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
title_sort leukocytospermia induces intraepithelial recruitment of dendritic cells and increases siv replication in colorectal tissue explants
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e148333ddf904b1ea51de80c040200ca
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AT rogerlegrand leukocytospermiainducesintraepithelialrecruitmentofdendriticcellsandincreasessivreplicationincolorectaltissueexplants
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