Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes

Abstract One of the main challenges for highly sensitive surface-enhanced Raman scattering (SERS) detection is the noise interference of fluorescence signals arising from the analyte molecules. Here we used three types of gold nanostars (GNSs) SERS probes treated by different surface modification me...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Feng Shan, Xiao-Yang Zhang, Xing-Chang Fu, Li-Jiang Zhang, Dan Su, Shan-Jiang Wang, Jing-Yuan Wu, Tong Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e14a8f05bd7c471891a63bf1142b6f51
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e14a8f05bd7c471891a63bf1142b6f51
record_format	dspace
spelling	oai:doaj.org-article:e14a8f05bd7c471891a63bf1142b6f512021-12-02T12:32:39ZInvestigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes10.1038/s41598-017-07311-82045-2322https://doaj.org/article/e14a8f05bd7c471891a63bf1142b6f512017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07311-8https://doaj.org/toc/2045-2322Abstract One of the main challenges for highly sensitive surface-enhanced Raman scattering (SERS) detection is the noise interference of fluorescence signals arising from the analyte molecules. Here we used three types of gold nanostars (GNSs) SERS probes treated by different surface modification methods to reveal the simultaneously existed Raman scattering enhancement and inhibiting fluorescence behaviors during the SERS detection process. As the distance between the metal nanostructures and the analyte molecules can be well controlled by these three surface modification methods, we demonstrated that the fluorescence signals can be either quenched or enhanced during the detection. We found that fluorescence quenching will occur when analyte molecules are closely contacted to the surface of GNSs, leading to a ~100 fold enhancement of the SERS sensitivity. An optimized Raman signal detection limit, as low as the level of 10−11 M, were achieved when Rhodamine 6 G were used as the analyte. The presented fluorescence-free GNSs SERS substrates with plentiful hot spots and controllable surface plasmon resonance wavelengths, fabricated using a cost-effective self-assembling method, can be very competitive candidates for high-sensitive SERS applications.Feng ShanXiao-Yang ZhangXing-Chang FuLi-Jiang ZhangDan SuShan-Jiang WangJing-Yuan WuTong ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Feng Shan Xiao-Yang Zhang Xing-Chang Fu Li-Jiang Zhang Dan Su Shan-Jiang Wang Jing-Yuan Wu Tong Zhang Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
description	Abstract One of the main challenges for highly sensitive surface-enhanced Raman scattering (SERS) detection is the noise interference of fluorescence signals arising from the analyte molecules. Here we used three types of gold nanostars (GNSs) SERS probes treated by different surface modification methods to reveal the simultaneously existed Raman scattering enhancement and inhibiting fluorescence behaviors during the SERS detection process. As the distance between the metal nanostructures and the analyte molecules can be well controlled by these three surface modification methods, we demonstrated that the fluorescence signals can be either quenched or enhanced during the detection. We found that fluorescence quenching will occur when analyte molecules are closely contacted to the surface of GNSs, leading to a ~100 fold enhancement of the SERS sensitivity. An optimized Raman signal detection limit, as low as the level of 10−11 M, were achieved when Rhodamine 6 G were used as the analyte. The presented fluorescence-free GNSs SERS substrates with plentiful hot spots and controllable surface plasmon resonance wavelengths, fabricated using a cost-effective self-assembling method, can be very competitive candidates for high-sensitive SERS applications.
format	article
author	Feng Shan Xiao-Yang Zhang Xing-Chang Fu Li-Jiang Zhang Dan Su Shan-Jiang Wang Jing-Yuan Wu Tong Zhang
author_facet	Feng Shan Xiao-Yang Zhang Xing-Chang Fu Li-Jiang Zhang Dan Su Shan-Jiang Wang Jing-Yuan Wu Tong Zhang
author_sort	Feng Shan
title	Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
title_short	Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
title_full	Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
title_fullStr	Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
title_full_unstemmed	Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes
title_sort	investigation of simultaneously existed raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as sers probes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e14a8f05bd7c471891a63bf1142b6f51
work_keys_str_mv	AT fengshan investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT xiaoyangzhang investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT xingchangfu investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT lijiangzhang investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT dansu investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT shanjiangwang investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT jingyuanwu investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes AT tongzhang investigationofsimultaneouslyexistedramanscatteringenhancementandinhibitingfluorescenceusingsurfacemodifiedgoldnanostarsassersprobes
_version_	1718394011736080384

Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes

Ejemplares similares