Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study report...
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2021
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oai:doaj.org-article:e153cd6734d8426ca2b32a1283f87e632021-11-30T04:14:17ZPotential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity1201-971210.1016/j.ijid.2021.09.035https://doaj.org/article/e153cd6734d8426ca2b32a1283f87e632021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221007396https://doaj.org/toc/1201-9712Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.Ana M CorreiaVítor BorgesJoana IsidroAna R LimaAlberto FernandesMaria Leonor GodinhoSílvia DuarteJosé FerrãoLuís VieiraJoão P GomesElsevierarticleSARS-CoV-2COVID-19Re-positivityInfectivityGenome sequencingInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 318-320 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
SARS-CoV-2 COVID-19 Re-positivity Infectivity Genome sequencing Infectious and parasitic diseases RC109-216 |
spellingShingle |
SARS-CoV-2 COVID-19 Re-positivity Infectivity Genome sequencing Infectious and parasitic diseases RC109-216 Ana M Correia Vítor Borges Joana Isidro Ana R Lima Alberto Fernandes Maria Leonor Godinho Sílvia Duarte José Ferrão Luís Vieira João P Gomes Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
description |
Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases. |
format |
article |
author |
Ana M Correia Vítor Borges Joana Isidro Ana R Lima Alberto Fernandes Maria Leonor Godinho Sílvia Duarte José Ferrão Luís Vieira João P Gomes |
author_facet |
Ana M Correia Vítor Borges Joana Isidro Ana R Lima Alberto Fernandes Maria Leonor Godinho Sílvia Duarte José Ferrão Luís Vieira João P Gomes |
author_sort |
Ana M Correia |
title |
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
title_short |
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
title_full |
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
title_fullStr |
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
title_full_unstemmed |
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity |
title_sort |
potential recurrence of covid-19 in a healthcare professional: sars-cov-2 genome sequencing confirms contagiousness after re-positivity |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/e153cd6734d8426ca2b32a1283f87e63 |
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