Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity

Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study report...

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Autores principales: Ana M Correia, Vítor Borges, Joana Isidro, Ana R Lima, Alberto Fernandes, Maria Leonor Godinho, Sílvia Duarte, José Ferrão, Luís Vieira, João P Gomes
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Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/e153cd6734d8426ca2b32a1283f87e63
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spelling oai:doaj.org-article:e153cd6734d8426ca2b32a1283f87e632021-11-30T04:14:17ZPotential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity1201-971210.1016/j.ijid.2021.09.035https://doaj.org/article/e153cd6734d8426ca2b32a1283f87e632021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221007396https://doaj.org/toc/1201-9712Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.Ana M CorreiaVítor BorgesJoana IsidroAna R LimaAlberto FernandesMaria Leonor GodinhoSílvia DuarteJosé FerrãoLuís VieiraJoão P GomesElsevierarticleSARS-CoV-2COVID-19Re-positivityInfectivityGenome sequencingInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 318-320 (2021)
institution DOAJ
collection DOAJ
language EN
topic SARS-CoV-2
COVID-19
Re-positivity
Infectivity
Genome sequencing
Infectious and parasitic diseases
RC109-216
spellingShingle SARS-CoV-2
COVID-19
Re-positivity
Infectivity
Genome sequencing
Infectious and parasitic diseases
RC109-216
Ana M Correia
Vítor Borges
Joana Isidro
Ana R Lima
Alberto Fernandes
Maria Leonor Godinho
Sílvia Duarte
José Ferrão
Luís Vieira
João P Gomes
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
description Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.
format article
author Ana M Correia
Vítor Borges
Joana Isidro
Ana R Lima
Alberto Fernandes
Maria Leonor Godinho
Sílvia Duarte
José Ferrão
Luís Vieira
João P Gomes
author_facet Ana M Correia
Vítor Borges
Joana Isidro
Ana R Lima
Alberto Fernandes
Maria Leonor Godinho
Sílvia Duarte
José Ferrão
Luís Vieira
João P Gomes
author_sort Ana M Correia
title Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_short Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_fullStr Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full_unstemmed Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_sort potential recurrence of covid-19 in a healthcare professional: sars-cov-2 genome sequencing confirms contagiousness after re-positivity
publisher Elsevier
publishDate 2021
url https://doaj.org/article/e153cd6734d8426ca2b32a1283f87e63
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