MAIT cells contribute to protection against lethal influenza infection in vivo

MAIT cells are abundant in the lungs and confer protection against bacterial pathogens. Whilst activation of these cells has been described during viral infections, here van Wilgenburg and colleagues show that in a murine model MAIT cells contribute to the protective host immune response to influenz...

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Autores principales:	Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J. Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nüssing, Sneha Sant, Zhongfang Wang, Criselle D’Souza, Xiaoxiao Jia, Catarina F. Almeida, Lyudmila Kostenko, Sidonia B. G. Eckle, Bronwyn S. Meehan, Axel Kallies, Dale I. Godfrey, Patrick C. Reading, Alexandra J. Corbett, James McCluskey, Paul Klenerman, Katherine Kedzierska, Timothy S. C. Hinks
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e15ac8dd044648a69319eb56458d539f
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spelling	oai:doaj.org-article:e15ac8dd044648a69319eb56458d539f2021-12-02T15:34:23ZMAIT cells contribute to protection against lethal influenza infection in vivo10.1038/s41467-018-07207-92041-1723https://doaj.org/article/e15ac8dd044648a69319eb56458d539f2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07207-9https://doaj.org/toc/2041-1723MAIT cells are abundant in the lungs and confer protection against bacterial pathogens. Whilst activation of these cells has been described during viral infections, here van Wilgenburg and colleagues show that in a murine model MAIT cells contribute to the protective host immune response to influenza virus infection.Bonnie van WilgenburgLiyen LohZhenjun ChenTroi J. PediongcoHuimeng WangMai ShiZhe ZhaoMarios KoutsakosSimone NüssingSneha SantZhongfang WangCriselle D’SouzaXiaoxiao JiaCatarina F. AlmeidaLyudmila KostenkoSidonia B. G. EckleBronwyn S. MeehanAxel KalliesDale I. GodfreyPatrick C. ReadingAlexandra J. CorbettJames McCluskeyPaul KlenermanKatherine KedzierskaTimothy S. C. HinksNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bonnie van Wilgenburg Liyen Loh Zhenjun Chen Troi J. Pediongco Huimeng Wang Mai Shi Zhe Zhao Marios Koutsakos Simone Nüssing Sneha Sant Zhongfang Wang Criselle D’Souza Xiaoxiao Jia Catarina F. Almeida Lyudmila Kostenko Sidonia B. G. Eckle Bronwyn S. Meehan Axel Kallies Dale I. Godfrey Patrick C. Reading Alexandra J. Corbett James McCluskey Paul Klenerman Katherine Kedzierska Timothy S. C. Hinks MAIT cells contribute to protection against lethal influenza infection in vivo
description	MAIT cells are abundant in the lungs and confer protection against bacterial pathogens. Whilst activation of these cells has been described during viral infections, here van Wilgenburg and colleagues show that in a murine model MAIT cells contribute to the protective host immune response to influenza virus infection.
format	article
author	Bonnie van Wilgenburg Liyen Loh Zhenjun Chen Troi J. Pediongco Huimeng Wang Mai Shi Zhe Zhao Marios Koutsakos Simone Nüssing Sneha Sant Zhongfang Wang Criselle D’Souza Xiaoxiao Jia Catarina F. Almeida Lyudmila Kostenko Sidonia B. G. Eckle Bronwyn S. Meehan Axel Kallies Dale I. Godfrey Patrick C. Reading Alexandra J. Corbett James McCluskey Paul Klenerman Katherine Kedzierska Timothy S. C. Hinks
author_facet	Bonnie van Wilgenburg Liyen Loh Zhenjun Chen Troi J. Pediongco Huimeng Wang Mai Shi Zhe Zhao Marios Koutsakos Simone Nüssing Sneha Sant Zhongfang Wang Criselle D’Souza Xiaoxiao Jia Catarina F. Almeida Lyudmila Kostenko Sidonia B. G. Eckle Bronwyn S. Meehan Axel Kallies Dale I. Godfrey Patrick C. Reading Alexandra J. Corbett James McCluskey Paul Klenerman Katherine Kedzierska Timothy S. C. Hinks
author_sort	Bonnie van Wilgenburg
title	MAIT cells contribute to protection against lethal influenza infection in vivo
title_short	MAIT cells contribute to protection against lethal influenza infection in vivo
title_full	MAIT cells contribute to protection against lethal influenza infection in vivo
title_fullStr	MAIT cells contribute to protection against lethal influenza infection in vivo
title_full_unstemmed	MAIT cells contribute to protection against lethal influenza infection in vivo
title_sort	mait cells contribute to protection against lethal influenza infection in vivo
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e15ac8dd044648a69319eb56458d539f
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MAIT cells contribute to protection against lethal influenza infection in vivo

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