Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA

Stephanie B Engelhard, Vandan Patel, Ashvini K Reddy Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA Background: The purpose of this study was to identify the causes, clinical features, and outcomes of intermediate uveitis, posterior uveitis, and panuveitis in patien...

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Autores principales:	Engelhard SB, Patel V, Reddy AK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e160f3c8feb741ba9768a1a1ba59ae21
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spelling	oai:doaj.org-article:e160f3c8feb741ba9768a1a1ba59ae212021-12-02T02:14:30ZIntermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA1177-5483https://doaj.org/article/e160f3c8feb741ba9768a1a1ba59ae212015-08-01T00:00:00Zhttp://www.dovepress.com/intermediate-uveitis-posterior-uveitis-and-panuveitis-in-the-mid-atlan-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Stephanie B Engelhard, Vandan Patel, Ashvini K Reddy Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA Background: The purpose of this study was to identify the causes, clinical features, and outcomes of intermediate uveitis, posterior uveitis, and panuveitis in patients managed in a mid-Atlantic tertiary care center.Methods: This was a retrospective observational study of intermediate uveitis, posterior uveitis, and panuveitis patients seen at the University of Virginia from 1984 to 2014. Results: One hundred and fifty-nine intermediate uveitis, posterior uveitis, and panuveitis patients (237 eyes) were identified. The patient population was 54.72% female; 67.30% of patients were Caucasian, and 22.01% were African–American. Mean age at diagnosis was 45.5 years. Mean duration of follow-up was 3.95 years. Mean number of visits to the clinic was 10.35. Of 491 uveitis patients, 26 (5.30%) had intermediate uveitis, 62 (12.60%) had posterior uveitis, and 71 (14.50%) had panuveitis. The leading diagnoses in the intermediate uveitis group were pars planitis (73.08%) and sarcoidosis (11.54%); toxoplasma uveitis (17.74%), multifocal choroiditis (14.52%), undifferentiated posterior uveitis (14.52%), and birdshot chorioretinitis (11.29%) in the posterior uveitis group; and undifferentiated panuveitis (29.58%), post-surgical panuveitis (18.31%), sarcoidosis (12.68%), acute retinal necrosis (12.68%), and toxoplasma uveitis (4.23%) in the panuveitis group. The most common treatment modalities included local steroids (57.23%) and systemic steroids (42.14%). Ocular hypertension was found in 38 patients (23.90%). Glaucoma surgery was performed in 18.24% of patients and cataract surgery in 21.38%. Mean best-corrected visual acuity was 0.66 logMAR at baseline across all anatomical locations and 0.57 logMAR at final follow-up. Best-corrected visual acuity improved or remained stable during follow-up in all groups. Conclusion: The most common diagnoses in our series by anatomical location were pars planitis (intermediate uveitis), toxoplasmosis (posterior uveitis), and undifferentiated uveitis (panuveitis). Panuveitis had significantly worse visual outcomes and higher rates of complications than did intermediate or posterior uveitis, a finding that confirms earlier reports. In this series, unilateral disease, regardless of anatomical location, was associated with poorer visual outcome, in contrast with the findings of other reports. Keywords: visual acuity, intraocular pressure, toxoplasmosis, acute retinal necrosis, toxoplasmosis, birdshot chorioretinitisEngelhard SBPatel VReddy AKDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1549-1555 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Engelhard SB Patel V Reddy AK Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
description	Stephanie B Engelhard, Vandan Patel, Ashvini K Reddy Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA Background: The purpose of this study was to identify the causes, clinical features, and outcomes of intermediate uveitis, posterior uveitis, and panuveitis in patients managed in a mid-Atlantic tertiary care center.Methods: This was a retrospective observational study of intermediate uveitis, posterior uveitis, and panuveitis patients seen at the University of Virginia from 1984 to 2014. Results: One hundred and fifty-nine intermediate uveitis, posterior uveitis, and panuveitis patients (237 eyes) were identified. The patient population was 54.72% female; 67.30% of patients were Caucasian, and 22.01% were African–American. Mean age at diagnosis was 45.5 years. Mean duration of follow-up was 3.95 years. Mean number of visits to the clinic was 10.35. Of 491 uveitis patients, 26 (5.30%) had intermediate uveitis, 62 (12.60%) had posterior uveitis, and 71 (14.50%) had panuveitis. The leading diagnoses in the intermediate uveitis group were pars planitis (73.08%) and sarcoidosis (11.54%); toxoplasma uveitis (17.74%), multifocal choroiditis (14.52%), undifferentiated posterior uveitis (14.52%), and birdshot chorioretinitis (11.29%) in the posterior uveitis group; and undifferentiated panuveitis (29.58%), post-surgical panuveitis (18.31%), sarcoidosis (12.68%), acute retinal necrosis (12.68%), and toxoplasma uveitis (4.23%) in the panuveitis group. The most common treatment modalities included local steroids (57.23%) and systemic steroids (42.14%). Ocular hypertension was found in 38 patients (23.90%). Glaucoma surgery was performed in 18.24% of patients and cataract surgery in 21.38%. Mean best-corrected visual acuity was 0.66 logMAR at baseline across all anatomical locations and 0.57 logMAR at final follow-up. Best-corrected visual acuity improved or remained stable during follow-up in all groups. Conclusion: The most common diagnoses in our series by anatomical location were pars planitis (intermediate uveitis), toxoplasmosis (posterior uveitis), and undifferentiated uveitis (panuveitis). Panuveitis had significantly worse visual outcomes and higher rates of complications than did intermediate or posterior uveitis, a finding that confirms earlier reports. In this series, unilateral disease, regardless of anatomical location, was associated with poorer visual outcome, in contrast with the findings of other reports. Keywords: visual acuity, intraocular pressure, toxoplasmosis, acute retinal necrosis, toxoplasmosis, birdshot chorioretinitis
format	article
author	Engelhard SB Patel V Reddy AK
author_facet	Engelhard SB Patel V Reddy AK
author_sort	Engelhard SB
title	Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
title_short	Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
title_full	Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
title_fullStr	Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
title_full_unstemmed	Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
title_sort	intermediate uveitis, posterior uveitis, and panuveitis in the mid-atlantic usa
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/e160f3c8feb741ba9768a1a1ba59ae21
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Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA

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