The effect of rosuvastatin in a murine model of influenza A infection.

The effect of rosuvastatin in a murine model of influenza A infection.

<h4>Rationale</h4>HMG-CoA reductase inhibitors such as rosuvastatin may have immunomodulatory and anti-inflammatory effects that may reduce the severity of influenza A infection. We hypothesized that rosuvastatin would decrease viral replication, attenuate lung injury, and improve mortal...

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Autores principales: Kathryn A Radigan, Daniela Urich, Alexander V Misharin, Sergio E Chiarella, Saul Soberanes, Angel Gonzalez, Harris Perlman, Richard G Wunderink, G R Scott Budinger, Gökhan M Mutlu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e1610579da42473e908243a65e720c16
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