Factors Required for Activation of Urease as a Virulence Determinant in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

Factors Required for Activation of Urease as a Virulence Determinant in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the brain and causing meningoencephalitis. Although urea is not required for synthesis of apourease encoded by URE1, the available nitrogen source affected the expression of URE1 as well as the level of the...

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Bibliographic Details
Main Authors: Arpita Singh, Robert J. Panting, Ashok Varma, Tomomi Saijo, Kevin J. Waldron, Ambrose Jong, Popchai Ngamskulrungroj, Yun C. Chang, Julian C. Rutherford, Kyung J. Kwon-Chung
Format: article
Language:EN
Published: American Society for Microbiology 2013
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/e1799b6ddd5e457a8165e02ca311d6d4
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