Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells
Abstract Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially increase the expansion and activation of CD8+ T cells by targeting CD4+ T cells. When autologous OCs were used t...
Enregistré dans:
Auteurs principaux: | Kawaljit Kaur, Meng-Wei Ko, Nick Ohanian, Jessica Cook, Anahid Jewett |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/e17d77d68b1d4c05bf67756c29ed0972 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells
par: Katherine E. Harris, et autres
Publié: (2021) -
Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer
par: Minhua Chen, et autres
Publié: (2021) -
Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
par: Marion Rolot, et autres
Publié: (2018) -
Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity
par: Fok-Moon Lum, et autres
Publié: (2018) -
CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease
par: L. Krabbendam, et autres
Publié: (2021)