Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells

Abstract Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially increase the expansion and activation of CD8+ T cells by targeting CD4+ T cells. When autologous OCs were used t...

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Bibliographic Details
Main Authors: Kawaljit Kaur, Meng-Wei Ko, Nick Ohanian, Jessica Cook, Anahid Jewett
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/e17d77d68b1d4c05bf67756c29ed0972
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